Fusion of Hsp70 to GFP Impairs Its Function and Causes Formation of Misfolded Protein Deposits under Mild Stress in Yeast
Protein misfolding is a common feature of aging, various diseases and stresses. Recent work has revealed that misfolded proteins can be gathered into specific compartments, which can limit their deleterious effects. Chaperones play a central role in the formation of these misfolded protein deposits...
Main Authors: | Erika V. Grosfeld, Anastasia Yu. Beizer, Alexander A. Dergalev, Michael O. Agaphonov, Alexander I. Alexandrov |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-08-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/16/12758 |
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