Suppressive activity of RGX-365 on HMGB1-mediated septic responses

Suppressive activity of RGX-365 on HMGB1-mediated septic responses

Abstract RGX-365 is the main fraction of black ginseng conmprising protopanaxatriol (PPT)-type rare ginsenosides (ginsenosides Rg4, Rg6, Rh4, Rh1, and Rg2). No studies on the antiseptic activity of RGX-365 have been reported. High mobility group box 1 (HMGB1) is recognized as a late mediator of seps...

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Bibliographic Details
Main Authors: Wonhwa Lee, Ji-Eun Kim, Sumin Yang, Bong-Seon Lee, Soo-Hyun Cho, Jee-Hyun Lee, Ga-Eun Choi, Eui Kyun Park, Gyu-Yong Song, Jong-Sup Bae
Format: Article
Language:English
Published: Universidade de São Paulo 2022-07-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
RGX-365
Permeability
HMGB1
Sepsis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100609&tlng=en

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