CircRNA inhibits DNA damage repair by interacting with host gene

CircRNA inhibits DNA damage repair by interacting with host gene

Abstract Background Deregulated circular RNAs (circRNAs) are associated with the development of cancer and therapy resistance. However, functional research of circRNAs mostly focus on potential miRNA or protein binding and more potential regulation of circRNA on host gene DNA in cancers are yet to b...

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Bibliographic Details
Main Authors: Xiaolong Xu, Jingwei Zhang, Yihao Tian, Yang Gao, Xin Dong, Wenbo Chen, Xiaoning Yuan, Weinan Yin, Jinjing Xu, Ke Chen, Chunjiang He, Lei Wei
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Molecular Cancer
Subjects:
Breast cancer
circRNA
DNA damage repair
R-loop
Host gene
Online Access:http://link.springer.com/article/10.1186/s12943-020-01246-x

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