Functional polymorphisms of the lncRNA H19 promoter region contribute to the cancer risk and clinical outcomes in advanced colorectal cancer

Functional polymorphisms of the lncRNA H19 promoter region contribute to the cancer risk and clinical outcomes in advanced colorectal cancer

Abstract Background The long non-coding RNA H19 plays critical roles in cancer occurrence, development, and progression. The present study is for the first time to evaluate the association of genetic variations in the H19 promoter region with advanced colorectal cancer (CRC) susceptibility, environm...

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Bibliographic Details
Main Authors: Wenyan Qin, Xiaodong Wang, Yilin Wang, Yalun Li, Qiuchen Chen, Xiaoyun Hu, Zhikun Wu, Pengfei Zhao, Shanqiong Li, Haishan Zhao, Weifan Yao, Jian Ding, Minjie Wei, Huizhe Wu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Cancer Cell International
Subjects:
H19
Genetic polymorphisms
Susceptibility
Colorectal cancer
Prognosis
Online Access:http://link.springer.com/article/10.1186/s12935-019-0895-x

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