Integrated single-cell RNA-seq analysis reveals the vital cell types and dynamic development signature of atherosclerosis

Integrated single-cell RNA-seq analysis reveals the vital cell types and dynamic development signature of atherosclerosis

Introduction: In the development of atherosclerosis, the remodeling of blood vessels is a key process involving plaque formation and rupture. So far, most reports mainly believe that macrophages, smooth muscle cells, and endothelial cells located at the intima and media of artery play the key role i...

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Bibliographic Details
Main Authors: Xiuli Shao, Xiuyang Hou, Xiaolin Zhang, Ruijia Zhang, Rongli Zhu, He Qi, Jianling Zheng, Xiaoling Guo, Rui Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Physiology
Subjects:
scRNA-seq
atherosclerosis
fibroblasts
fibrosis
remodeling
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1118239/full

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