In silico analysis to identify miR-1271-5p/PLCB4 (phospholipase C Beta 4) axis mediated oxaliplatin resistance in metastatic colorectal cancer

In silico analysis to identify miR-1271-5p/PLCB4 (phospholipase C Beta 4) axis mediated oxaliplatin resistance in metastatic colorectal cancer

Abstract Oxaliplatin (OXA) is the first-line chemotherapy drug for metastatic colorectal cancer (mCRC), and the emergence of drug resistance is a major clinical challenge. Although there have been numerous studies on OXA resistance, but its underlying molecular mechanisms are still unclear. This stu...

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Bibliographic Details
Main Authors:	Cheng-Chin Lee, Ai-Wei Lee, Po-Li Wei, Yi-Shin Liu, Yu-Jia Chang, Chien-Yu Huang
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-03-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-023-31331-2

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