The Genetic Diversity and Dysfunctionality of Catalase Associated with a Worse Outcome in Crohn’s Disease

The Genetic Diversity and Dysfunctionality of Catalase Associated with a Worse Outcome in Crohn’s Disease

Chronic gut inflammation in Crohn’s disease (CD) is associated with an increase in oxidative stress and an imbalance of antioxidant enzymes. We have previously shown that catalase (CAT) activity is permanently inhibited by CD. The purpose of the study was to determine whether there is any relationsh...

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Bibliographic Details
Main Authors: Marisa Iborra, Inés Moret, Enrique Busó, José Luis García-Giménez, Elena Ricart, Javier P. Gisbert, Eduard Cabré, Maria Esteve, Lucía Márquez-Mosquera, Esther García-Planella, Jordi Guardiola, Federico V. Pallardó, Carolina Serena, Francisco Algaba-Chueca, Eugeni Domenech, Pilar Nos, Belén Beltrán
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
catalase
inflammatory bowel disease
Crohn’s disease
oxidative stress
antioxidant genes
Online Access:https://www.mdpi.com/1422-0067/23/24/15881

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