Sophoridine exerts tumor-suppressive activities via promoting ESRRG-mediated β-catenin degradation in gastric cancer

Sophoridine exerts tumor-suppressive activities via promoting ESRRG-mediated β-catenin degradation in gastric cancer

Abstract Background As a natural alkaloid product isolated from Sophora alopecuroides. L, Sophoridine reshapes gastric cancer immune microenvironment via inhibiting chemotaxis and M2 polarization of tumor-associated macrophages (TAMs). However, the exact effects and underlying mechanism of Sophoridi...

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Bibliographic Details
Main Authors: Zhiyang Peng, Qing Guan, Jianfei Luo, Wenhong Deng, Jiasheng Liu, Ruicheng Yan, Weixing Wang
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Cancer
Subjects:
Gastric cancer
Sophoridine
ESRRG
β-Catenin
Online Access:http://link.springer.com/article/10.1186/s12885-020-07067-x

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http://link.springer.com/article/10.1186/s12885-020-07067-x

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