Progression of axial spondyloarthritis

The spectrum of bone lesions in axial spondyloarthritis is of great interest. With inflammation and mechanical influence concurrence in the background, both tissue gain and tissue loss in a particular bone area can occur simultaneously. Moreover, if vertebral bone mass loss, perhaps, can be easily e...

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Main Authors: Sh. F. Erdes, T. V. Korotaeva
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2021-06-01
Series:Современная ревматология
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/1141
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author Sh. F. Erdes
T. V. Korotaeva
author_facet Sh. F. Erdes
T. V. Korotaeva
author_sort Sh. F. Erdes
collection DOAJ
description The spectrum of bone lesions in axial spondyloarthritis is of great interest. With inflammation and mechanical influence concurrence in the background, both tissue gain and tissue loss in a particular bone area can occur simultaneously. Moreover, if vertebral bone mass loss, perhaps, can be easily explained by chronic systemic inflammation, the reason of its gain, observed in axial spondyloarthritis remains a mystery. It is unclear whether it is a consequence of enhanced recovery processes after injury, adaptation to altered mechanical stress, response to inflammatory cells activation or cytokines, produced by them, or changes in Wnt signaling pathways (for example). Whether these factors act individually or collectively is also unclear.
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spelling doaj.art-9996ca9deabb49abb6f9c744adc0eae72023-03-13T08:39:28ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2021-06-0115371410.14412/1996-7012-2021-3-7-142355Progression of axial spondyloarthritisSh. F. Erdes0T. V. Korotaeva1ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»The spectrum of bone lesions in axial spondyloarthritis is of great interest. With inflammation and mechanical influence concurrence in the background, both tissue gain and tissue loss in a particular bone area can occur simultaneously. Moreover, if vertebral bone mass loss, perhaps, can be easily explained by chronic systemic inflammation, the reason of its gain, observed in axial spondyloarthritis remains a mystery. It is unclear whether it is a consequence of enhanced recovery processes after injury, adaptation to altered mechanical stress, response to inflammatory cells activation or cytokines, produced by them, or changes in Wnt signaling pathways (for example). Whether these factors act individually or collectively is also unclear.https://mrj.ima-press.net/mrj/article/view/1141аксиальный спондилоартританкилозирующий спондилитбиомаркерыпрогрессированиенообразование костной ткани
spellingShingle Sh. F. Erdes
T. V. Korotaeva
Progression of axial spondyloarthritis
Современная ревматология
аксиальный спондилоартрит
анкилозирующий спондилит
биомаркеры
прогрессирование
нообразование костной ткани
title Progression of axial spondyloarthritis
title_full Progression of axial spondyloarthritis
title_fullStr Progression of axial spondyloarthritis
title_full_unstemmed Progression of axial spondyloarthritis
title_short Progression of axial spondyloarthritis
title_sort progression of axial spondyloarthritis
topic аксиальный спондилоартрит
анкилозирующий спондилит
биомаркеры
прогрессирование
нообразование костной ткани
url https://mrj.ima-press.net/mrj/article/view/1141
work_keys_str_mv AT shferdes progressionofaxialspondyloarthritis
AT tvkorotaeva progressionofaxialspondyloarthritis