Progression of axial spondyloarthritis
The spectrum of bone lesions in axial spondyloarthritis is of great interest. With inflammation and mechanical influence concurrence in the background, both tissue gain and tissue loss in a particular bone area can occur simultaneously. Moreover, if vertebral bone mass loss, perhaps, can be easily e...
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Format: | Article |
Language: | Russian |
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IMA-PRESS LLC
2021-06-01
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Series: | Современная ревматология |
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Online Access: | https://mrj.ima-press.net/mrj/article/view/1141 |
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author | Sh. F. Erdes T. V. Korotaeva |
author_facet | Sh. F. Erdes T. V. Korotaeva |
author_sort | Sh. F. Erdes |
collection | DOAJ |
description | The spectrum of bone lesions in axial spondyloarthritis is of great interest. With inflammation and mechanical influence concurrence in the background, both tissue gain and tissue loss in a particular bone area can occur simultaneously. Moreover, if vertebral bone mass loss, perhaps, can be easily explained by chronic systemic inflammation, the reason of its gain, observed in axial spondyloarthritis remains a mystery. It is unclear whether it is a consequence of enhanced recovery processes after injury, adaptation to altered mechanical stress, response to inflammatory cells activation or cytokines, produced by them, or changes in Wnt signaling pathways (for example). Whether these factors act individually or collectively is also unclear. |
first_indexed | 2024-04-10T02:06:35Z |
format | Article |
id | doaj.art-9996ca9deabb49abb6f9c744adc0eae7 |
institution | Directory Open Access Journal |
issn | 1996-7012 2310-158X |
language | Russian |
last_indexed | 2024-04-10T02:06:35Z |
publishDate | 2021-06-01 |
publisher | IMA-PRESS LLC |
record_format | Article |
series | Современная ревматология |
spelling | doaj.art-9996ca9deabb49abb6f9c744adc0eae72023-03-13T08:39:28ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2021-06-0115371410.14412/1996-7012-2021-3-7-142355Progression of axial spondyloarthritisSh. F. Erdes0T. V. Korotaeva1ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»The spectrum of bone lesions in axial spondyloarthritis is of great interest. With inflammation and mechanical influence concurrence in the background, both tissue gain and tissue loss in a particular bone area can occur simultaneously. Moreover, if vertebral bone mass loss, perhaps, can be easily explained by chronic systemic inflammation, the reason of its gain, observed in axial spondyloarthritis remains a mystery. It is unclear whether it is a consequence of enhanced recovery processes after injury, adaptation to altered mechanical stress, response to inflammatory cells activation or cytokines, produced by them, or changes in Wnt signaling pathways (for example). Whether these factors act individually or collectively is also unclear.https://mrj.ima-press.net/mrj/article/view/1141аксиальный спондилоартританкилозирующий спондилитбиомаркерыпрогрессированиенообразование костной ткани |
spellingShingle | Sh. F. Erdes T. V. Korotaeva Progression of axial spondyloarthritis Современная ревматология аксиальный спондилоартрит анкилозирующий спондилит биомаркеры прогрессирование нообразование костной ткани |
title | Progression of axial spondyloarthritis |
title_full | Progression of axial spondyloarthritis |
title_fullStr | Progression of axial spondyloarthritis |
title_full_unstemmed | Progression of axial spondyloarthritis |
title_short | Progression of axial spondyloarthritis |
title_sort | progression of axial spondyloarthritis |
topic | аксиальный спондилоартрит анкилозирующий спондилит биомаркеры прогрессирование нообразование костной ткани |
url | https://mrj.ima-press.net/mrj/article/view/1141 |
work_keys_str_mv | AT shferdes progressionofaxialspondyloarthritis AT tvkorotaeva progressionofaxialspondyloarthritis |