Ovarian Germ Cell Tumor – Histopathological and statistical analysis

<p><strong>Background: </strong>Ovarian cancers are common among females. The ovarian tumors are classified according to its histogenesis. In the present study, we analyzed the germ cell ovarian tumors reported in our institute.</p> <p><strong>Materials and Method...

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Main Authors: A Ghosh, D Magar Gharti, B Sathian, R Narasimhan, Op Talwar
Format: Article
Language:English
Published: Association of Clinical Pathologists of Nepal 2013-10-01
Series:Journal of Pathology of Nepal
Subjects:
Online Access:http://www.nepjol.info/index.php/JPN/article/view/8990
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author A Ghosh
D Magar Gharti
B Sathian
R Narasimhan
Op Talwar
author_facet A Ghosh
D Magar Gharti
B Sathian
R Narasimhan
Op Talwar
author_sort A Ghosh
collection DOAJ
description <p><strong>Background: </strong>Ovarian cancers are common among females. The ovarian tumors are classified according to its histogenesis. In the present study, we analyzed the germ cell ovarian tumors reported in our institute.</p> <p><strong>Materials and Methods: </strong>This study was a hospital based retrospective study. All ovarian germ cell tumor reported from Jan 2001 to Feb 2013 were retrieved and analyzed. The specimens were routinely processed and the slides were stained with H&amp;E and special stains wherever required.</p> <p><strong>Results: </strong>A total of 340 cases of ovarian tumors were reported and 150 cases (44%) were of germ cell origin. We had 137 cases of benign and 13 cases of malignant germ cell tumors. Most common subtype was mature cystic teratoma comprising 125 cases. Among the malignant cases, the most common was immature teratoma (5 cases). Age range in our series was from 8 to 82 years (mean 28 years). The most common age group affected was 21-30 years. Most of the malignant cases (76.9%) were in less than 30 years. Among the malignant cases majority (84.6%) were more than 10 cm in size. None of the malignant germ cell tumors were bilateral.</p> <p><strong>Conclusion: </strong>Among germ cell tumors of ovary, mature cystic teratoma is the most common tumor and malignant subtypes are uncommon. Malignant tumors tend to occur in younger age group.</p> <p>DOI: <a href="http://dx.doi.org/10.3126/jpn.v3i6.8990">http://dx.doi.org/10.3126/jpn.v3i6.8990</a></p> <p>Journal of Pathology of Nepal (2013) Vol. <strong>3</strong>, 441-446</p>
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spelling doaj.art-9998bff460784126832637cb976fd51b2022-12-21T18:14:57ZengAssociation of Clinical Pathologists of NepalJournal of Pathology of Nepal2091-07972091-09082013-10-013644144610.3126/jpn.v3i6.89907233Ovarian Germ Cell Tumor – Histopathological and statistical analysisA Ghosh0D Magar Gharti1B Sathian2R Narasimhan3Op Talwar4Department of Pathology, Manipal College of Medical Sciences, PokharaDepartment of Pathology, Manipal College of Medical Sciences, PokharaDepartment of Community Medicine, Manipal College of Medical Sciences, PokharaDepartment of Pathology, Manipal College of Medical Sciences, PokharaDepartment of Pathology, Manipal College of Medical Sciences, Pokhara<p><strong>Background: </strong>Ovarian cancers are common among females. The ovarian tumors are classified according to its histogenesis. In the present study, we analyzed the germ cell ovarian tumors reported in our institute.</p> <p><strong>Materials and Methods: </strong>This study was a hospital based retrospective study. All ovarian germ cell tumor reported from Jan 2001 to Feb 2013 were retrieved and analyzed. The specimens were routinely processed and the slides were stained with H&amp;E and special stains wherever required.</p> <p><strong>Results: </strong>A total of 340 cases of ovarian tumors were reported and 150 cases (44%) were of germ cell origin. We had 137 cases of benign and 13 cases of malignant germ cell tumors. Most common subtype was mature cystic teratoma comprising 125 cases. Among the malignant cases, the most common was immature teratoma (5 cases). Age range in our series was from 8 to 82 years (mean 28 years). The most common age group affected was 21-30 years. Most of the malignant cases (76.9%) were in less than 30 years. Among the malignant cases majority (84.6%) were more than 10 cm in size. None of the malignant germ cell tumors were bilateral.</p> <p><strong>Conclusion: </strong>Among germ cell tumors of ovary, mature cystic teratoma is the most common tumor and malignant subtypes are uncommon. Malignant tumors tend to occur in younger age group.</p> <p>DOI: <a href="http://dx.doi.org/10.3126/jpn.v3i6.8990">http://dx.doi.org/10.3126/jpn.v3i6.8990</a></p> <p>Journal of Pathology of Nepal (2013) Vol. <strong>3</strong>, 441-446</p>http://www.nepjol.info/index.php/JPN/article/view/8990Germ cell tumorOvarian tumorOvaryTeratoma
spellingShingle A Ghosh
D Magar Gharti
B Sathian
R Narasimhan
Op Talwar
Ovarian Germ Cell Tumor – Histopathological and statistical analysis
Journal of Pathology of Nepal
Germ cell tumor
Ovarian tumor
Ovary
Teratoma
title Ovarian Germ Cell Tumor – Histopathological and statistical analysis
title_full Ovarian Germ Cell Tumor – Histopathological and statistical analysis
title_fullStr Ovarian Germ Cell Tumor – Histopathological and statistical analysis
title_full_unstemmed Ovarian Germ Cell Tumor – Histopathological and statistical analysis
title_short Ovarian Germ Cell Tumor – Histopathological and statistical analysis
title_sort ovarian germ cell tumor histopathological and statistical analysis
topic Germ cell tumor
Ovarian tumor
Ovary
Teratoma
url http://www.nepjol.info/index.php/JPN/article/view/8990
work_keys_str_mv AT aghosh ovariangermcelltumorhistopathologicalandstatisticalanalysis
AT dmagargharti ovariangermcelltumorhistopathologicalandstatisticalanalysis
AT bsathian ovariangermcelltumorhistopathologicalandstatisticalanalysis
AT rnarasimhan ovariangermcelltumorhistopathologicalandstatisticalanalysis
AT optalwar ovariangermcelltumorhistopathologicalandstatisticalanalysis