Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis

Combined treatment with an angiotensin-converting enzyme (ACE) inhibitor and an angiotensin II (Ang II) receptor blocker (ARB) has been suggested in order to achieve a more complete blockade of the renin-angiotensin-aldosterone system in cardiovascular and renal disease. The present report describes...

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Main Authors: Anne-Lise Kamper, Arne Høj Nielsen, Niels Bækgaard, Svend Just
Format: Article
Language:English
Published: SAGE Publications 2002-06-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2002.016
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author Anne-Lise Kamper
Arne Høj Nielsen
Niels Bækgaard
Svend Just
author_facet Anne-Lise Kamper
Arne Høj Nielsen
Niels Bækgaard
Svend Just
author_sort Anne-Lise Kamper
collection DOAJ
description Combined treatment with an angiotensin-converting enzyme (ACE) inhibitor and an angiotensin II (Ang II) receptor blocker (ARB) has been suggested in order to achieve a more complete blockade of the renin-angiotensin-aldosterone system in cardiovascular and renal disease. The present report describes a case of acute renal graft dysfunction following the addition of an ARB to existing ACE inhibition. This unmasked an unknown iliac artery stenosis. The case indicates a possible important role of Ang II generated by non-ACE pathways in this situation.
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spelling doaj.art-999e6371f9b448fbb64c27c841e068652024-03-03T02:50:23ZengSAGE PublicationsJournal of the Renin-Angiotensin-Aldosterone System1470-32032002-06-01310.3317/jraas.2002.016Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosisAnne-Lise KamperArne Høj NielsenNiels BækgaardSvend JustCombined treatment with an angiotensin-converting enzyme (ACE) inhibitor and an angiotensin II (Ang II) receptor blocker (ARB) has been suggested in order to achieve a more complete blockade of the renin-angiotensin-aldosterone system in cardiovascular and renal disease. The present report describes a case of acute renal graft dysfunction following the addition of an ARB to existing ACE inhibition. This unmasked an unknown iliac artery stenosis. The case indicates a possible important role of Ang II generated by non-ACE pathways in this situation.https://doi.org/10.3317/jraas.2002.016
spellingShingle Anne-Lise Kamper
Arne Høj Nielsen
Niels Bækgaard
Svend Just
Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis
Journal of the Renin-Angiotensin-Aldosterone System
title Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis
title_full Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis
title_fullStr Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis
title_full_unstemmed Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis
title_short Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis
title_sort renal graft failure after addition of an angiotensin ii receptor antagonist to an angiotensin converting enzyme inhibitor unmasking of an unknown iliac artery stenosis
url https://doi.org/10.3317/jraas.2002.016
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