Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis
Combined treatment with an angiotensin-converting enzyme (ACE) inhibitor and an angiotensin II (Ang II) receptor blocker (ARB) has been suggested in order to achieve a more complete blockade of the renin-angiotensin-aldosterone system in cardiovascular and renal disease. The present report describes...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publications
2002-06-01
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Series: | Journal of the Renin-Angiotensin-Aldosterone System |
Online Access: | https://doi.org/10.3317/jraas.2002.016 |
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author | Anne-Lise Kamper Arne Høj Nielsen Niels Bækgaard Svend Just |
author_facet | Anne-Lise Kamper Arne Høj Nielsen Niels Bækgaard Svend Just |
author_sort | Anne-Lise Kamper |
collection | DOAJ |
description | Combined treatment with an angiotensin-converting enzyme (ACE) inhibitor and an angiotensin II (Ang II) receptor blocker (ARB) has been suggested in order to achieve a more complete blockade of the renin-angiotensin-aldosterone system in cardiovascular and renal disease. The present report describes a case of acute renal graft dysfunction following the addition of an ARB to existing ACE inhibition. This unmasked an unknown iliac artery stenosis. The case indicates a possible important role of Ang II generated by non-ACE pathways in this situation. |
first_indexed | 2024-03-07T17:04:01Z |
format | Article |
id | doaj.art-999e6371f9b448fbb64c27c841e06865 |
institution | Directory Open Access Journal |
issn | 1470-3203 |
language | English |
last_indexed | 2024-03-07T17:04:01Z |
publishDate | 2002-06-01 |
publisher | SAGE Publications |
record_format | Article |
series | Journal of the Renin-Angiotensin-Aldosterone System |
spelling | doaj.art-999e6371f9b448fbb64c27c841e068652024-03-03T02:50:23ZengSAGE PublicationsJournal of the Renin-Angiotensin-Aldosterone System1470-32032002-06-01310.3317/jraas.2002.016Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosisAnne-Lise KamperArne Høj NielsenNiels BækgaardSvend JustCombined treatment with an angiotensin-converting enzyme (ACE) inhibitor and an angiotensin II (Ang II) receptor blocker (ARB) has been suggested in order to achieve a more complete blockade of the renin-angiotensin-aldosterone system in cardiovascular and renal disease. The present report describes a case of acute renal graft dysfunction following the addition of an ARB to existing ACE inhibition. This unmasked an unknown iliac artery stenosis. The case indicates a possible important role of Ang II generated by non-ACE pathways in this situation.https://doi.org/10.3317/jraas.2002.016 |
spellingShingle | Anne-Lise Kamper Arne Høj Nielsen Niels Bækgaard Svend Just Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis Journal of the Renin-Angiotensin-Aldosterone System |
title | Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis |
title_full | Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis |
title_fullStr | Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis |
title_full_unstemmed | Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis |
title_short | Renal graft failure after addition of an angiotensin II receptor antagonist to an angiotensin-converting enzyme inhibitor: unmasking of an unknown iliac artery stenosis |
title_sort | renal graft failure after addition of an angiotensin ii receptor antagonist to an angiotensin converting enzyme inhibitor unmasking of an unknown iliac artery stenosis |
url | https://doi.org/10.3317/jraas.2002.016 |
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