Exploring the shared molecular mechanisms between systemic lupus erythematosus and primary Sjögren’s syndrome based on integrated bioinformatics and single-cell RNA-seq analysis

Exploring the shared molecular mechanisms between systemic lupus erythematosus and primary Sjögren’s syndrome based on integrated bioinformatics and single-cell RNA-seq analysis

BackgroundSystemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS) are common systemic autoimmune diseases that share a wide range of clinical manifestations and serological features. This study investigates genes, signaling pathways, and transcription factors (TFs) shared between SLE...

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Bibliographic Details
Main Authors: Yanling Cui, Huina Zhang, Zhen Wang, Bangdong Gong, Hisham Al-Ward, Yaxuan Deng, Orion Fan, Junbang Wang, Wenmin Zhu, Yi Eve Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
primary Sjögren’s syndrome
bioinformatics
hub genes
TFs
scRNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1212330/full

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