Zika virus infection in a pregnant Canadian traveler with congenital fetal malformations noted by ultrasonography at 14-weeks gestation

Abstract Background Following emergence of Zika virus in the Americas, a devastating new congenital syndrome has been documented, leading to significant morbidity among Zika-infected fetuses and neonates. Case presentation A 29-year-old pregnant woman infected with Zika virus at 9-weeks gestation in...

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Bibliographic Details
Main Authors: Kevin L. Schwartz, Tiffany Chan, Nanky Rai, Kellie E. Murphy, Wendy Whittle, Michael A. Drebot, Jonathan Gubbay, Andrea K. Boggild
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Tropical Diseases, Travel Medicine and Vaccines
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40794-018-0062-8
Description
Summary:Abstract Background Following emergence of Zika virus in the Americas, a devastating new congenital syndrome has been documented, leading to significant morbidity among Zika-infected fetuses and neonates. Case presentation A 29-year-old pregnant woman infected with Zika virus at 9-weeks gestation in Trinidad presented with one-month of fever, headache, and myalgia with persistent viremia. Significant fetal abnormalities were identified at 14-week ultrasound, which is the earliest ultrasound to describe a severely affected fetus following Zika virus infection to our knowledge. Conclusions We discuss the implications of prolonged maternal viremia and the spectrum of congenital Zika syndrome detectable by fetal ultrasound.
ISSN:2055-0936