Zika virus infection in a pregnant Canadian traveler with congenital fetal malformations noted by ultrasonography at 14-weeks gestation

Abstract Background Following emergence of Zika virus in the Americas, a devastating new congenital syndrome has been documented, leading to significant morbidity among Zika-infected fetuses and neonates. Case presentation A 29-year-old pregnant woman infected with Zika virus at 9-weeks gestation in...

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Main Authors: Kevin L. Schwartz, Tiffany Chan, Nanky Rai, Kellie E. Murphy, Wendy Whittle, Michael A. Drebot, Jonathan Gubbay, Andrea K. Boggild
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Tropical Diseases, Travel Medicine and Vaccines
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40794-018-0062-8
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author Kevin L. Schwartz
Tiffany Chan
Nanky Rai
Kellie E. Murphy
Wendy Whittle
Michael A. Drebot
Jonathan Gubbay
Andrea K. Boggild
author_facet Kevin L. Schwartz
Tiffany Chan
Nanky Rai
Kellie E. Murphy
Wendy Whittle
Michael A. Drebot
Jonathan Gubbay
Andrea K. Boggild
author_sort Kevin L. Schwartz
collection DOAJ
description Abstract Background Following emergence of Zika virus in the Americas, a devastating new congenital syndrome has been documented, leading to significant morbidity among Zika-infected fetuses and neonates. Case presentation A 29-year-old pregnant woman infected with Zika virus at 9-weeks gestation in Trinidad presented with one-month of fever, headache, and myalgia with persistent viremia. Significant fetal abnormalities were identified at 14-week ultrasound, which is the earliest ultrasound to describe a severely affected fetus following Zika virus infection to our knowledge. Conclusions We discuss the implications of prolonged maternal viremia and the spectrum of congenital Zika syndrome detectable by fetal ultrasound.
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spelling doaj.art-99a2a9505d274509a1966adcdf57f5432022-12-22T01:06:45ZengBMCTropical Diseases, Travel Medicine and Vaccines2055-09362018-04-01411710.1186/s40794-018-0062-8Zika virus infection in a pregnant Canadian traveler with congenital fetal malformations noted by ultrasonography at 14-weeks gestationKevin L. Schwartz0Tiffany Chan1Nanky Rai2Kellie E. Murphy3Wendy Whittle4Michael A. Drebot5Jonathan Gubbay6Andrea K. Boggild7Public Health OntarioDivision of Infectious Diseases, Department of Medicine, University of TorontoDepartment of Family and Community Medicine, University of TorontoDepartment of Obstetrics and Gynecology, University of TorontoDepartment of Obstetrics and Gynecology, University of TorontoNational Microbiology Laboratory, Public Health Agency of CanadaPublic Health OntarioPublic Health OntarioAbstract Background Following emergence of Zika virus in the Americas, a devastating new congenital syndrome has been documented, leading to significant morbidity among Zika-infected fetuses and neonates. Case presentation A 29-year-old pregnant woman infected with Zika virus at 9-weeks gestation in Trinidad presented with one-month of fever, headache, and myalgia with persistent viremia. Significant fetal abnormalities were identified at 14-week ultrasound, which is the earliest ultrasound to describe a severely affected fetus following Zika virus infection to our knowledge. Conclusions We discuss the implications of prolonged maternal viremia and the spectrum of congenital Zika syndrome detectable by fetal ultrasound.http://link.springer.com/article/10.1186/s40794-018-0062-8ArbovirusCongenital infectionsFetal sonographyPregnancy and travelZika virus
spellingShingle Kevin L. Schwartz
Tiffany Chan
Nanky Rai
Kellie E. Murphy
Wendy Whittle
Michael A. Drebot
Jonathan Gubbay
Andrea K. Boggild
Zika virus infection in a pregnant Canadian traveler with congenital fetal malformations noted by ultrasonography at 14-weeks gestation
Tropical Diseases, Travel Medicine and Vaccines
Arbovirus
Congenital infections
Fetal sonography
Pregnancy and travel
Zika virus
title Zika virus infection in a pregnant Canadian traveler with congenital fetal malformations noted by ultrasonography at 14-weeks gestation
title_full Zika virus infection in a pregnant Canadian traveler with congenital fetal malformations noted by ultrasonography at 14-weeks gestation
title_fullStr Zika virus infection in a pregnant Canadian traveler with congenital fetal malformations noted by ultrasonography at 14-weeks gestation
title_full_unstemmed Zika virus infection in a pregnant Canadian traveler with congenital fetal malformations noted by ultrasonography at 14-weeks gestation
title_short Zika virus infection in a pregnant Canadian traveler with congenital fetal malformations noted by ultrasonography at 14-weeks gestation
title_sort zika virus infection in a pregnant canadian traveler with congenital fetal malformations noted by ultrasonography at 14 weeks gestation
topic Arbovirus
Congenital infections
Fetal sonography
Pregnancy and travel
Zika virus
url http://link.springer.com/article/10.1186/s40794-018-0062-8
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