PrImary decompressive Craniectomy in AneurySmal Subarachnoid hemOrrhage (PICASSO) trial: study protocol for a randomized controlled trial

PrImary decompressive Craniectomy in AneurySmal Subarachnoid hemOrrhage (PICASSO) trial: study protocol for a randomized controlled trial

Abstract Background Poor-grade aneurysmal subarachnoid hemorrhage (SAH) is associated with poor neurological outcome and high mortality. A major factor influencing morbidity and mortality is brain swelling in the acute phase. Decompressive craniectomy (DC) is currently used as an option in order to...

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Bibliographic Details
Main Authors: Erdem Güresir, Tim Lampmann, Simon Brandecker, Marcus Czabanka, Rolf Fimmers, Jens Gempt, Patrick Haas, Amer Haj, Ramazan Jabbarli, Darius Kalasauskas, Ralph König, Dorothee Mielke, Robert Németh, Marvin Darkwah Oppong, Andrej Pala, Vincent Prinz, Florian Ringel, Constantin Roder, Veit Rohde, Karl-Michael Schebesch, Arthur Wagner, Christoph Coch, Hartmut Vatter
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Trials
Subjects:
Early brain injury
Intracranial pressure
Decompressive craniectomy
Subarachnoid hemorrhage
Intracranial aneurysm
Randomized trial
Online Access:https://doi.org/10.1186/s13063-022-06969-4

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