Nimesulide-induced acute biliary tract injury and renal failure in a kitten: a case report
A 3-month-old male kitten was presented to our clinic with malaise, vomiting and jaundice. In the anamnesis, we learned that the cat had a history of anorexia, sneezing, and nasal discharge and that the owner had administered 100 mg/day (t.i.d.) nimesulide orally for three days. In the laboratory st...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Czech Academy of Agricultural Sciences
2008-03-01
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| Series: | Veterinární Medicína |
| Subjects: | |
| Online Access: | https://vetmed.agriculturejournals.cz/artkey/vet-200803-0007_nimesulide-induced-acute-biliary-tract-injury-and-renal-failure-in-a-kitten-a-case-report.php |
| _version_ | 1797897676641009664 |
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| author | M.K. Borku M. Guzel M.C. Karakurum K. Ural S. Aktas |
| author_facet | M.K. Borku M. Guzel M.C. Karakurum K. Ural S. Aktas |
| author_sort | M.K. Borku |
| collection | DOAJ |
| description | A 3-month-old male kitten was presented to our clinic with malaise, vomiting and jaundice. In the anamnesis, we learned that the cat had a history of anorexia, sneezing, and nasal discharge and that the owner had administered 100 mg/day (t.i.d.) nimesulide orally for three days. In the laboratory study, high levels of serum alkaline phosphatase, γ-glutamyl transtransferase, total bilirubin, direct bilirubin, indirect bilirubin, urea, and creatinine were detected. All the clinical signs and laboratory abnormalities returned to normal levels after cessation of the nimesulide and supportive treatment. In this case, clinical and laboratory findings were thought to be compatible with nimesulide-induced acute biliary injury and renal failure. This case report indicates that the household pets are at risk of toxic drugs administered by their owners and great caution should be taken in administering NSAIDs in cats. |
| first_indexed | 2024-04-10T08:02:04Z |
| format | Article |
| id | doaj.art-99a372838ef04276b9c41c7360db4c93 |
| institution | Directory Open Access Journal |
| issn | 0375-8427 1805-9392 |
| language | English |
| last_indexed | 2024-04-10T08:02:04Z |
| publishDate | 2008-03-01 |
| publisher | Czech Academy of Agricultural Sciences |
| record_format | Article |
| series | Veterinární Medicína |
| spelling | doaj.art-99a372838ef04276b9c41c7360db4c932023-02-23T03:49:34ZengCzech Academy of Agricultural SciencesVeterinární Medicína0375-84271805-93922008-03-0153316917210.17221/1938-VETMEDvet-200803-0007Nimesulide-induced acute biliary tract injury and renal failure in a kitten: a case reportM.K. Borku0M. Guzel1M.C. Karakurum2K. Ural3S. Aktas4Faculty of Veterinary Medicine, Ankara University, Ankara, TurkeyFaculty of Veterinary Medicine, Mustafa Kemal University, Hatay, TurkeyFaculty of Veterinary Medicine, Mehmet Akif Ersoy University, Burdur, TurkeyFaculty of Veterinary Medicine, Ankara University, Ankara, TurkeyFaculty of Veterinary Medicine, Ataturk University, Erzurum, TurkeyA 3-month-old male kitten was presented to our clinic with malaise, vomiting and jaundice. In the anamnesis, we learned that the cat had a history of anorexia, sneezing, and nasal discharge and that the owner had administered 100 mg/day (t.i.d.) nimesulide orally for three days. In the laboratory study, high levels of serum alkaline phosphatase, γ-glutamyl transtransferase, total bilirubin, direct bilirubin, indirect bilirubin, urea, and creatinine were detected. All the clinical signs and laboratory abnormalities returned to normal levels after cessation of the nimesulide and supportive treatment. In this case, clinical and laboratory findings were thought to be compatible with nimesulide-induced acute biliary injury and renal failure. This case report indicates that the household pets are at risk of toxic drugs administered by their owners and great caution should be taken in administering NSAIDs in cats.https://vetmed.agriculturejournals.cz/artkey/vet-200803-0007_nimesulide-induced-acute-biliary-tract-injury-and-renal-failure-in-a-kitten-a-case-report.phpnonsteroidal anti-inflammatory drugnimesulidebiliary injuryrenal failurekitten |
| spellingShingle | M.K. Borku M. Guzel M.C. Karakurum K. Ural S. Aktas Nimesulide-induced acute biliary tract injury and renal failure in a kitten: a case report Veterinární Medicína nonsteroidal anti-inflammatory drug nimesulide biliary injury renal failure kitten |
| title | Nimesulide-induced acute biliary tract injury and renal failure in a kitten: a case report |
| title_full | Nimesulide-induced acute biliary tract injury and renal failure in a kitten: a case report |
| title_fullStr | Nimesulide-induced acute biliary tract injury and renal failure in a kitten: a case report |
| title_full_unstemmed | Nimesulide-induced acute biliary tract injury and renal failure in a kitten: a case report |
| title_short | Nimesulide-induced acute biliary tract injury and renal failure in a kitten: a case report |
| title_sort | nimesulide induced acute biliary tract injury and renal failure in a kitten a case report |
| topic | nonsteroidal anti-inflammatory drug nimesulide biliary injury renal failure kitten |
| url | https://vetmed.agriculturejournals.cz/artkey/vet-200803-0007_nimesulide-induced-acute-biliary-tract-injury-and-renal-failure-in-a-kitten-a-case-report.php |
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