Current Concepts and Future Applications of Non-Invasive Functional and Anatomical Evaluation of Coronary Artery Disease

Over the last decades, significant advances have been achieved in the treatment of coronary artery disease (CAD). Proper non-invasive diagnosis and appropriate management based on functional information and the extension of ischemia or viability remain the cornerstone in the fight against adverse CA...

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Main Authors: Evangelos Oikonomou, Panagiotis Theofilis, Stamatios Lampsas, Ourania Katsarou, Konstantinos Kalogeras, Georgios Marinos, Aikaterini Tsatsaragkou, Artemis Anastasiou, Antonios Lysandrou, Maria-Ioanna Gounaridi, Ioannis Gialamas, Michael-Andrew Vavuranakis, Dimitris Tousoulis, Manolis Vavuranakis, Gerasimos Siasos
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Life
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Online Access:https://www.mdpi.com/2075-1729/12/11/1803
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author Evangelos Oikonomou
Panagiotis Theofilis
Stamatios Lampsas
Ourania Katsarou
Konstantinos Kalogeras
Georgios Marinos
Aikaterini Tsatsaragkou
Artemis Anastasiou
Antonios Lysandrou
Maria-Ioanna Gounaridi
Ioannis Gialamas
Michael-Andrew Vavuranakis
Dimitris Tousoulis
Manolis Vavuranakis
Gerasimos Siasos
author_facet Evangelos Oikonomou
Panagiotis Theofilis
Stamatios Lampsas
Ourania Katsarou
Konstantinos Kalogeras
Georgios Marinos
Aikaterini Tsatsaragkou
Artemis Anastasiou
Antonios Lysandrou
Maria-Ioanna Gounaridi
Ioannis Gialamas
Michael-Andrew Vavuranakis
Dimitris Tousoulis
Manolis Vavuranakis
Gerasimos Siasos
author_sort Evangelos Oikonomou
collection DOAJ
description Over the last decades, significant advances have been achieved in the treatment of coronary artery disease (CAD). Proper non-invasive diagnosis and appropriate management based on functional information and the extension of ischemia or viability remain the cornerstone in the fight against adverse CAD events. Stress echocardiography and single photon emission computed tomography are often used for the evaluation of ischemia. Advancements in non-invasive imaging modalities such as computed tomography (CT) coronary angiography and cardiac magnetic resonance imaging (MRI) have not only allowed non-invasive imaging of coronary artery lumen but also provide additional functional information. Other characteristics regarding the plaque morphology can be further evaluated with the latest modalities achieving a morpho-functional evaluation of CAD. Advances in the utilization of positron emission tomography (PET), as well as software advancements especially regarding cardiac CT, may provide additional prognostic information to a more evidence-based treatment decision. Since the armamentarium on non-invasive imaging modalities has evolved, the knowledge of the capabilities and limitations of each imaging modality should be evaluated in a case-by-case basis to achieve the best diagnosis and treatment decision. In this review article, we present the most recent advances in the noninvasive anatomical and functional evaluation of CAD.
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spelling doaj.art-99a4e01366cf420ca6b1372605c163f12023-11-24T05:31:11ZengMDPI AGLife2075-17292022-11-011211180310.3390/life12111803Current Concepts and Future Applications of Non-Invasive Functional and Anatomical Evaluation of Coronary Artery DiseaseEvangelos Oikonomou0Panagiotis Theofilis1Stamatios Lampsas2Ourania Katsarou3Konstantinos Kalogeras4Georgios Marinos5Aikaterini Tsatsaragkou6Artemis Anastasiou7Antonios Lysandrou8Maria-Ioanna Gounaridi9Ioannis Gialamas10Michael-Andrew Vavuranakis11Dimitris Tousoulis12Manolis Vavuranakis13Gerasimos Siasos143rd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Sotiria Chest Disease Hospital, 11527 Athens, Greece1st Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippokration General Hospital, 11527 Athens, Greece3rd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Sotiria Chest Disease Hospital, 11527 Athens, Greece3rd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Sotiria Chest Disease Hospital, 11527 Athens, Greece3rd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Sotiria Chest Disease Hospital, 11527 Athens, GreeceDepartment of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece3rd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Sotiria Chest Disease Hospital, 11527 Athens, Greece3rd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Sotiria Chest Disease Hospital, 11527 Athens, Greece3rd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Sotiria Chest Disease Hospital, 11527 Athens, Greece3rd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Sotiria Chest Disease Hospital, 11527 Athens, Greece3rd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Sotiria Chest Disease Hospital, 11527 Athens, Greece3rd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Sotiria Chest Disease Hospital, 11527 Athens, Greece1st Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Hippokration General Hospital, 11527 Athens, Greece3rd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Sotiria Chest Disease Hospital, 11527 Athens, Greece3rd Department of Cardiology, Medical School, National and Kapodistrian University of Athens, Sotiria Chest Disease Hospital, 11527 Athens, GreeceOver the last decades, significant advances have been achieved in the treatment of coronary artery disease (CAD). Proper non-invasive diagnosis and appropriate management based on functional information and the extension of ischemia or viability remain the cornerstone in the fight against adverse CAD events. Stress echocardiography and single photon emission computed tomography are often used for the evaluation of ischemia. Advancements in non-invasive imaging modalities such as computed tomography (CT) coronary angiography and cardiac magnetic resonance imaging (MRI) have not only allowed non-invasive imaging of coronary artery lumen but also provide additional functional information. Other characteristics regarding the plaque morphology can be further evaluated with the latest modalities achieving a morpho-functional evaluation of CAD. Advances in the utilization of positron emission tomography (PET), as well as software advancements especially regarding cardiac CT, may provide additional prognostic information to a more evidence-based treatment decision. Since the armamentarium on non-invasive imaging modalities has evolved, the knowledge of the capabilities and limitations of each imaging modality should be evaluated in a case-by-case basis to achieve the best diagnosis and treatment decision. In this review article, we present the most recent advances in the noninvasive anatomical and functional evaluation of CAD.https://www.mdpi.com/2075-1729/12/11/1803coronary artery diseasenon-invasiveanatomicalfunctionalatherosclerotic lesion
spellingShingle Evangelos Oikonomou
Panagiotis Theofilis
Stamatios Lampsas
Ourania Katsarou
Konstantinos Kalogeras
Georgios Marinos
Aikaterini Tsatsaragkou
Artemis Anastasiou
Antonios Lysandrou
Maria-Ioanna Gounaridi
Ioannis Gialamas
Michael-Andrew Vavuranakis
Dimitris Tousoulis
Manolis Vavuranakis
Gerasimos Siasos
Current Concepts and Future Applications of Non-Invasive Functional and Anatomical Evaluation of Coronary Artery Disease
Life
coronary artery disease
non-invasive
anatomical
functional
atherosclerotic lesion
title Current Concepts and Future Applications of Non-Invasive Functional and Anatomical Evaluation of Coronary Artery Disease
title_full Current Concepts and Future Applications of Non-Invasive Functional and Anatomical Evaluation of Coronary Artery Disease
title_fullStr Current Concepts and Future Applications of Non-Invasive Functional and Anatomical Evaluation of Coronary Artery Disease
title_full_unstemmed Current Concepts and Future Applications of Non-Invasive Functional and Anatomical Evaluation of Coronary Artery Disease
title_short Current Concepts and Future Applications of Non-Invasive Functional and Anatomical Evaluation of Coronary Artery Disease
title_sort current concepts and future applications of non invasive functional and anatomical evaluation of coronary artery disease
topic coronary artery disease
non-invasive
anatomical
functional
atherosclerotic lesion
url https://www.mdpi.com/2075-1729/12/11/1803
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