High Dual Expression of the Biomarkers CD44v6/α2β1 and CD44v6/PD-L1 Indicate Early Recurrence after Colorectal Hepatic Metastasectomy

High Dual Expression of the Biomarkers CD44v6/α2β1 and CD44v6/PD-L1 Indicate Early Recurrence after Colorectal Hepatic Metastasectomy

Considering the biology of CRC, distant metastases might support the identification of high-risk patients for early recurrence and targeted therapy. Expression of a panel of druggable, metastasis-related biomarkers was immunohistochemically analyzed in 53 liver (LM) and 15 lung metastases (LuM) and...

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Bibliographic Details
Main Authors: Friederike Wrana, Katharina Dötzer, Martin Prüfer, Jens Werner, Barbara Mayer
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cancers
Subjects:
colorectal cancer
liver metastases
lung metastases
protein biomarker
dual expression
early recurrence
Online Access:https://www.mdpi.com/2072-6694/14/8/1939

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