Different Ectopic Hoxa2 Expression Levels in Mouse Cranial Neural Crest Cells Result in Distinct Craniofacial Anomalies and Homeotic Phenotypes

Different Ectopic Hoxa2 Expression Levels in Mouse Cranial Neural Crest Cells Result in Distinct Craniofacial Anomalies and Homeotic Phenotypes

Providing appropriate positional identity and patterning information to distinct rostrocaudal subpopulations of cranial neural crest cells (CNCCs) is central to vertebrate craniofacial morphogenesis. <i>Hox</i> genes are not expressed in frontonasal and first pharyngeal arch (PA1) CNCCs,...

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Bibliographic Details
Main Authors: Taro Kitazawa, Maryline Minoux, Sebastien Ducret, Filippo M. Rijli
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Journal of Developmental Biology
Subjects:
<i>Hox</i> genes
Hoxa2
Hoxa5
cranial neural crest cells
gain-of-function
craniofacial morphogenesis
Online Access:https://www.mdpi.com/2221-3759/10/1/9

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https://www.mdpi.com/2221-3759/10/1/9

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