The Surgical Management of Proximal Femoral Metastases: A Narrative Review

The proximal femur is a common location for the development of bony metastatic disease. Metastatic bone disease in this location can cause debilitating pain, pathologic fractures, reduced quality of life, anemia or hypercalcemia. A thorough history, physical examination and preoperative investigatio...

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Main Authors: Daniel Axelrod, Aaron M. Gazendam, Michelle Ghert
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Current Oncology
Subjects:
Online Access:https://www.mdpi.com/1718-7729/28/5/320
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author Daniel Axelrod
Aaron M. Gazendam
Michelle Ghert
author_facet Daniel Axelrod
Aaron M. Gazendam
Michelle Ghert
author_sort Daniel Axelrod
collection DOAJ
description The proximal femur is a common location for the development of bony metastatic disease. Metastatic bone disease in this location can cause debilitating pain, pathologic fractures, reduced quality of life, anemia or hypercalcemia. A thorough history, physical examination and preoperative investigations are required to ensure accurate diagnosis and prognosis. The goals of surgical management is to provide pain relief and return to function with a construct that provides stability to allow for immediate weightbearing. Current surgical treatment options include intramedullary nailing, hemiarthroplasty or total hip arthroplasty and endoprosthetic reconstructions. Oligometastatic renal cell carcinoma must be given special consideration as tumor resection and reconstruction has survival benefit. Both tumor and patient characteristics must be taken into account before deciding on the appropriate surgical intervention.
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spelling doaj.art-99ad4592ab404b1ab0b353385a08a7982023-11-22T17:54:55ZengMDPI AGCurrent Oncology1198-00521718-77292021-09-012853748375710.3390/curroncol28050320The Surgical Management of Proximal Femoral Metastases: A Narrative ReviewDaniel Axelrod0Aaron M. Gazendam1Michelle Ghert2Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON L8N 4A6, CanadaDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON L8N 4A6, CanadaDivision of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON L8N 4A6, CanadaThe proximal femur is a common location for the development of bony metastatic disease. Metastatic bone disease in this location can cause debilitating pain, pathologic fractures, reduced quality of life, anemia or hypercalcemia. A thorough history, physical examination and preoperative investigations are required to ensure accurate diagnosis and prognosis. The goals of surgical management is to provide pain relief and return to function with a construct that provides stability to allow for immediate weightbearing. Current surgical treatment options include intramedullary nailing, hemiarthroplasty or total hip arthroplasty and endoprosthetic reconstructions. Oligometastatic renal cell carcinoma must be given special consideration as tumor resection and reconstruction has survival benefit. Both tumor and patient characteristics must be taken into account before deciding on the appropriate surgical intervention.https://www.mdpi.com/1718-7729/28/5/320metastatic bone diseaseproximal femur metastasesendoprosthesis
spellingShingle Daniel Axelrod
Aaron M. Gazendam
Michelle Ghert
The Surgical Management of Proximal Femoral Metastases: A Narrative Review
Current Oncology
metastatic bone disease
proximal femur metastases
endoprosthesis
title The Surgical Management of Proximal Femoral Metastases: A Narrative Review
title_full The Surgical Management of Proximal Femoral Metastases: A Narrative Review
title_fullStr The Surgical Management of Proximal Femoral Metastases: A Narrative Review
title_full_unstemmed The Surgical Management of Proximal Femoral Metastases: A Narrative Review
title_short The Surgical Management of Proximal Femoral Metastases: A Narrative Review
title_sort surgical management of proximal femoral metastases a narrative review
topic metastatic bone disease
proximal femur metastases
endoprosthesis
url https://www.mdpi.com/1718-7729/28/5/320
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