Study of bleeding disorders (hemophilia) in children in Beni-Suef university hospital

The goal of this study is to study the clinical spectrum of hemophiliac children (age <18 years) in Beni-Suef university hospital. A cross-sectional study conducted in the pediatric hematology clinic of Beni-Suef university hospital, over a period of 12 months. Out of a total of 112 cases enrolle...

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Main Authors: Dalia Kamal, Dina Ezzat, Rehab Lashin
Format: Article
Language:English
Published: Beni-Suef University, Faculty of Medicine 2022-10-01
Series:Egyptian Journal of Medical Research
Subjects:
Online Access:https://ejmr.journals.ekb.eg/article_275102_9361fe695f7f74f9db2d21e9b44b9ef5.pdf
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author Dalia Kamal
Dina Ezzat
Rehab Lashin
author_facet Dalia Kamal
Dina Ezzat
Rehab Lashin
author_sort Dalia Kamal
collection DOAJ
description The goal of this study is to study the clinical spectrum of hemophiliac children (age <18 years) in Beni-Suef university hospital. A cross-sectional study conducted in the pediatric hematology clinic of Beni-Suef university hospital, over a period of 12 months. Out of a total of 112 cases enrolled, 91% were diagnosed as hemophilia A. While (9%) were diagnosed as hemophilia B. Positive family history was found in (46%) of cases. The mean age of onset of symptoms and diagnosis was 1.7 ± 1.4 and 3.8 ± 3.8 years, respectively. ), the most common bleeding symptom was bruises (86.5), the most serious was intracranial hemorrhage (9.6%). While haemarthrosis was in (7.7%).Conclusion: Occurrence of posttraumatic bleeds and gum bleeds in an otherwise normal child should warn the clinician for evaluation of hemophilia. Hemophilias are distributed worldwide and have heterogeneous presentation depending upon the disease severity. Knowledge of the spectrum of presentation of hemophilia in the local population helps in early diagnosis and planning of management.
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spelling doaj.art-99af54a1edf84a1cb9ae6d059c30a1fd2023-02-27T17:41:52ZengBeni-Suef University, Faculty of MedicineEgyptian Journal of Medical Research2682-43962682-440X2022-10-013425426110.21608/ejmr.2021.100335.1148275102Study of bleeding disorders (hemophilia) in children in Beni-Suef university hospitalDalia Kamal0Dina Ezzat1Rehab Lashin2Depatrement of Pediatrics, Faculty of Medicine, Beni-Suef University, EgyptDepatrement of Pediatrics, Faculty of Medicine, Beni-Suef University, EgyptDepatrement of Clinical and Chemical Pathology, Faculty of Medicine, Beni-Suef University, Egypt.The goal of this study is to study the clinical spectrum of hemophiliac children (age <18 years) in Beni-Suef university hospital. A cross-sectional study conducted in the pediatric hematology clinic of Beni-Suef university hospital, over a period of 12 months. Out of a total of 112 cases enrolled, 91% were diagnosed as hemophilia A. While (9%) were diagnosed as hemophilia B. Positive family history was found in (46%) of cases. The mean age of onset of symptoms and diagnosis was 1.7 ± 1.4 and 3.8 ± 3.8 years, respectively. ), the most common bleeding symptom was bruises (86.5), the most serious was intracranial hemorrhage (9.6%). While haemarthrosis was in (7.7%).Conclusion: Occurrence of posttraumatic bleeds and gum bleeds in an otherwise normal child should warn the clinician for evaluation of hemophilia. Hemophilias are distributed worldwide and have heterogeneous presentation depending upon the disease severity. Knowledge of the spectrum of presentation of hemophilia in the local population helps in early diagnosis and planning of management.https://ejmr.journals.ekb.eg/article_275102_9361fe695f7f74f9db2d21e9b44b9ef5.pdfcross section studyhemarthrosishemophilia
spellingShingle Dalia Kamal
Dina Ezzat
Rehab Lashin
Study of bleeding disorders (hemophilia) in children in Beni-Suef university hospital
Egyptian Journal of Medical Research
cross section study
hemarthrosis
hemophilia
title Study of bleeding disorders (hemophilia) in children in Beni-Suef university hospital
title_full Study of bleeding disorders (hemophilia) in children in Beni-Suef university hospital
title_fullStr Study of bleeding disorders (hemophilia) in children in Beni-Suef university hospital
title_full_unstemmed Study of bleeding disorders (hemophilia) in children in Beni-Suef university hospital
title_short Study of bleeding disorders (hemophilia) in children in Beni-Suef university hospital
title_sort study of bleeding disorders hemophilia in children in beni suef university hospital
topic cross section study
hemarthrosis
hemophilia
url https://ejmr.journals.ekb.eg/article_275102_9361fe695f7f74f9db2d21e9b44b9ef5.pdf
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