Intestinal Metagenomes and Metabolomes in Healthy Young Males: Inactivity and Hypoxia Generated Negative Physiological Symptoms Precede Microbial Dysbiosis

Intestinal Metagenomes and Metabolomes in Healthy Young Males: Inactivity and Hypoxia Generated Negative Physiological Symptoms Precede Microbial Dysbiosis

We explored the metagenomic, metabolomic and trace metal makeup of intestinal microbiota and environment in healthy male participants during the run-in (5 day) and the following three 21-day interventions: normoxic bedrest (NBR), hypoxic bedrest (HBR) and hypoxic ambulation (HAmb) which were carried...

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Bibliographic Details
Main Authors: Robert Šket, Tadej Debevec, Susanne Kublik, Michael Schloter, Anne Schoeller, Boštjan Murovec, Katarina Vogel Mikuš, Damjan Makuc, Klemen Pečnik, Janez Plavec, Igor B. Mekjavić, Ola Eiken, Zala Prevoršek, Blaž Stres
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Physiology
Subjects:
metagenome
metabolome
human gut
microbiome
dysbiosis
exercise
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00198/full

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