Hypoxia represses FOXF1 in lung endothelial cells through HIF-1α

Hypoxia represses FOXF1 in lung endothelial cells through HIF-1α

Introduction: Forkhead Box F1 (FOXF1) transcription factor plays a critical role in lung angiogenesis during embryonic development and lung repair after injury. FOXF1 expression is decreased in endothelial cells after lung injury; however, molecular mechanisms responsible for the FOXF1 transcript ch...

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Bibliographic Details
Main Authors: Anusha Acharya, Fenghua Bian, Jose Gomez-Arroyo, Kimberly A. Wagner, Vladimir V. Kalinichenko, Tanya V. Kalin
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Physiology
Subjects:
lung
endothelial cells
hypoxia
FOXF1
HIF-1α
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1309155/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1309155/full

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