Reg-1α Promotes Differentiation of Cortical Progenitors via Its N-Terminal Active Domain

Reg-1α Promotes Differentiation of Cortical Progenitors via Its N-Terminal Active Domain

Reg-1α belongs to the Reg family of small, secreted proteins expressed in both pancreas and nervous system. Reg-1α is composed of two domains, an insoluble C-type lectin domain and a short soluble N-terminal peptide, which is released from the molecule upon proteolytic N-terminal processing, althoug...

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Bibliographic Details
Main Authors: Marjorie Varilh, Isabelle Acquatella-Tran Van Ba, Michelle Silhol, Francisco Nieto-Lopez, Mireille Moussaed, Marie-Christine Lebart, Paola Bovolenta, Jean-Michel Verdier, Mireille Rossel, Anne Marcilhac, Françoise Trousse
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
neural progenitors
Reg-1α
Extl3
axon elongation
differentiation
GSK-3β
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00681/full

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