The antiproliferative potential and mechanism of action of metformin in MCF-7 cells

The antiproliferative potential and mechanism of action of metformin in MCF-7 cells

Aim: The current study aimed to investigate the potential antiproliferative activity of metformin, the effective concentration range, and the mechanism of action. Materials & methods: Human breast cancer cells, MCF-7 were treated with a serial dilution of metformin (10–150 μM) for 24 and 48 h. P...

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Bibliographic Details
Main Authors:	Zhibek Bekezhankyzy, Sholpan Nurzhan, Nurken Berdigaliyev, Shynggys Sergazy, Tilektes Maulenkul, Mohamad Aljofan
Format:	Article
Language:	English
Published:	Future Science Ltd 2023-06-01
Series:	Future Science OA
Subjects:	antiproliferative apoptosis autophagy breast cancer metformin
Online Access:	https://www.future-science.com/doi/10.2144/fsoa-2022-0080

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