Determination of sensitivity to antibiotics of Campilobacter jejuni and Campilobacter coli isolated from human feces
Background/Aim. One of the most important bacterial zoonosis is campylobacteriosis. Human disease is mostly caused by thermophilic Campylobacter spp: Campylobacter jejuni (C. jejuni), Campylobacter coli (C. coli), Campylobacter lari (C. lari) and Campylobacter upsaliensis (C. upsaliensis). Campyloba...
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defance, Serbia
2009-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500901049T.pdf |
| _version_ | 1811299561291907072 |
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| author | Tambur Zoran Miljković-Selimović Biljana Bokonjić Dubravko |
| author_facet | Tambur Zoran Miljković-Selimović Biljana Bokonjić Dubravko |
| author_sort | Tambur Zoran |
| collection | DOAJ |
| description | Background/Aim. One of the most important bacterial zoonosis is campylobacteriosis. Human disease is mostly caused by thermophilic Campylobacter spp: Campylobacter jejuni (C. jejuni), Campylobacter coli (C. coli), Campylobacter lari (C. lari) and Campylobacter upsaliensis (C. upsaliensis). Campylobacteriosis is a mild and self-healing disorder. In patients with more severe and prolonged forms, an antibiotic treatment is recommended. Recommended drugs are erythromycin, ciprofloxacin, tetracyclin, chloramphenicol and ampicillin. Lately, an increase of Campylobacter genus resistance to antibiotics mostly used in therapy is an annoying evidence. The rise coincided with the beginning of antibiotic use, especially quinolones, in veterinary medicine. The aim of the study was to isolate and identify thermophilic Campylobacter spp. from human feces and to determine their sensitivity to antibiotics and hemotherapeutics mostly used in campylobacteriosis treatment. Methods. Sensitivity to erythromycin, tetracyclin, ampicillin, chloramphenicol and ciprofloxacin of 24 strains of Campylobacter spp. isolated from humans was investigated by E-test. Results. Seventeen C. jejuni and seven C. coli strains were investigated. Six (25%) out of 24 C. jejuni and C. coli investigated strains were resistant to ampicillin and seven (29.2%) were resistant to tetracycline. Twelve (50%) C. jejuni and C. coli investigated strains were resistant to ciprofloxacin. C. jejuni was more resistant (52.9%). Four (23.5%) C. jejuni strains were resistant to erythromycin and 11.7% to choramphenicol. None of C. coli strains were resistant to both chloramphenicol and erytromycin. Conclusons. Testing sensitivity to erythromycin, tetracycline, ampicillin, chloramphenicol and ciprofloxacin demonstrated a rather high resistance frequency of C. jejuni and C. coli strains isolated from humans. C. jejuni strains were more resistant than those of C. coli. |
| first_indexed | 2024-04-13T06:37:41Z |
| format | Article |
| id | doaj.art-99b2d299030c421497fd5308fc6eba62 |
| institution | Directory Open Access Journal |
| issn | 0042-8450 |
| language | English |
| last_indexed | 2024-04-13T06:37:41Z |
| publishDate | 2009-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-99b2d299030c421497fd5308fc6eba622022-12-22T02:57:50ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502009-01-01661495210.2298/VSP0901049TDetermination of sensitivity to antibiotics of Campilobacter jejuni and Campilobacter coli isolated from human fecesTambur ZoranMiljković-Selimović BiljanaBokonjić DubravkoBackground/Aim. One of the most important bacterial zoonosis is campylobacteriosis. Human disease is mostly caused by thermophilic Campylobacter spp: Campylobacter jejuni (C. jejuni), Campylobacter coli (C. coli), Campylobacter lari (C. lari) and Campylobacter upsaliensis (C. upsaliensis). Campylobacteriosis is a mild and self-healing disorder. In patients with more severe and prolonged forms, an antibiotic treatment is recommended. Recommended drugs are erythromycin, ciprofloxacin, tetracyclin, chloramphenicol and ampicillin. Lately, an increase of Campylobacter genus resistance to antibiotics mostly used in therapy is an annoying evidence. The rise coincided with the beginning of antibiotic use, especially quinolones, in veterinary medicine. The aim of the study was to isolate and identify thermophilic Campylobacter spp. from human feces and to determine their sensitivity to antibiotics and hemotherapeutics mostly used in campylobacteriosis treatment. Methods. Sensitivity to erythromycin, tetracyclin, ampicillin, chloramphenicol and ciprofloxacin of 24 strains of Campylobacter spp. isolated from humans was investigated by E-test. Results. Seventeen C. jejuni and seven C. coli strains were investigated. Six (25%) out of 24 C. jejuni and C. coli investigated strains were resistant to ampicillin and seven (29.2%) were resistant to tetracycline. Twelve (50%) C. jejuni and C. coli investigated strains were resistant to ciprofloxacin. C. jejuni was more resistant (52.9%). Four (23.5%) C. jejuni strains were resistant to erythromycin and 11.7% to choramphenicol. None of C. coli strains were resistant to both chloramphenicol and erytromycin. Conclusons. Testing sensitivity to erythromycin, tetracycline, ampicillin, chloramphenicol and ciprofloxacin demonstrated a rather high resistance frequency of C. jejuni and C. coli strains isolated from humans. C. jejuni strains were more resistant than those of C. coli.http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500901049T.pdfcampylobacterhumansanti-bacterial agentsdrug resistanceveterinary medicine |
| spellingShingle | Tambur Zoran Miljković-Selimović Biljana Bokonjić Dubravko Determination of sensitivity to antibiotics of Campilobacter jejuni and Campilobacter coli isolated from human feces Vojnosanitetski Pregled campylobacter humans anti-bacterial agents drug resistance veterinary medicine |
| title | Determination of sensitivity to antibiotics of Campilobacter jejuni and Campilobacter coli isolated from human feces |
| title_full | Determination of sensitivity to antibiotics of Campilobacter jejuni and Campilobacter coli isolated from human feces |
| title_fullStr | Determination of sensitivity to antibiotics of Campilobacter jejuni and Campilobacter coli isolated from human feces |
| title_full_unstemmed | Determination of sensitivity to antibiotics of Campilobacter jejuni and Campilobacter coli isolated from human feces |
| title_short | Determination of sensitivity to antibiotics of Campilobacter jejuni and Campilobacter coli isolated from human feces |
| title_sort | determination of sensitivity to antibiotics of campilobacter jejuni and campilobacter coli isolated from human feces |
| topic | campylobacter humans anti-bacterial agents drug resistance veterinary medicine |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500901049T.pdf |
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