Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case
Lithium is among the mainstays of treatment for bipolar disorder. Bariatric surgery can considerably change the oral bioavailability of drugs, particularly lithium. In this review, a 36-year-old male patient is described, who presented with lithium toxicity, including neurologic and gastric symptoms...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Association of Psychiatric Pharmacists
2022-06-01
|
| Series: | Mental Health Clinician |
| Subjects: | |
| Online Access: | https://theijpt.org/doi/pdf/10.9740/mhc.2022.06.214 |
| _version_ | 1797383406028324864 |
|---|---|
| author | Shahana Ayub, MD Sundas Saboor, MD Sadia Usmani, MD Sana Javed, MD Gauvain Kankeu Tonpouwo, MD Saeed Ahmed, MD |
| author_facet | Shahana Ayub, MD Sundas Saboor, MD Sadia Usmani, MD Sana Javed, MD Gauvain Kankeu Tonpouwo, MD Saeed Ahmed, MD |
| author_sort | Shahana Ayub, MD |
| collection | DOAJ |
| description | Lithium is among the mainstays of treatment for bipolar disorder. Bariatric surgery can considerably change the oral bioavailability of drugs, particularly lithium. In this review, a 36-year-old male patient is described, who presented with lithium toxicity, including neurologic and gastric symptoms after undergoing Roux-en-Y gastric bypass. The mechanism of lithium toxicity is discussed; recommendations for clinicians regarding lithium use in postsurgical patients are provided; and previous case reports of lithium toxicity post-gastric bypass surgery are analyzed. Awareness and education of lithium absorption changes postbariatric surgery is essential for optimal patient care. Close clinical and drug concentration level monitoring is warranted. |
| first_indexed | 2024-03-08T21:20:29Z |
| format | Article |
| id | doaj.art-99b5fc8a2f404ec3aeb8682faf1c3b9d |
| institution | Directory Open Access Journal |
| issn | 2168-9709 |
| language | English |
| last_indexed | 2024-03-08T21:20:29Z |
| publishDate | 2022-06-01 |
| publisher | American Association of Psychiatric Pharmacists |
| record_format | Article |
| series | Mental Health Clinician |
| spelling | doaj.art-99b5fc8a2f404ec3aeb8682faf1c3b9d2023-12-21T11:47:29ZengAmerican Association of Psychiatric PharmacistsMental Health Clinician2168-97092022-06-0112321421810.9740/mhc.2022.06.214i2168-9709-12-03-214Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative caseShahana Ayub, MD0https://orcid.org/0000-0002-6196-3543Sundas Saboor, MD1https://orcid.org/0000-0002-2112-3152Sadia Usmani, MD2https://orcid.org/0000-0003-2151-5874Sana Javed, MD3https://orcid.org/0000-0002-8384-2144Gauvain Kankeu Tonpouwo, MD4https://orcid.org/0000-0002-2981-4484Saeed Ahmed, MD5https://orcid.org/0000-0002-9483-23551 Psychiatrist, Cornerstone Family Health, Newburgh, New York2 Physician, Khyber Medical College, Peshawar, Khyber Pakhtunkhwa, Pakistan3 Physician, Dow University of Health Sciences, Karachi, Sindh, Pakistan4 Physician, Nishtar Medical University, Multan, Punjab, Pakistan5 Physician, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo6 Addiction Psychiatrist, Rutland Regional Medical Center, Rutland, VermontLithium is among the mainstays of treatment for bipolar disorder. Bariatric surgery can considerably change the oral bioavailability of drugs, particularly lithium. In this review, a 36-year-old male patient is described, who presented with lithium toxicity, including neurologic and gastric symptoms after undergoing Roux-en-Y gastric bypass. The mechanism of lithium toxicity is discussed; recommendations for clinicians regarding lithium use in postsurgical patients are provided; and previous case reports of lithium toxicity post-gastric bypass surgery are analyzed. Awareness and education of lithium absorption changes postbariatric surgery is essential for optimal patient care. Close clinical and drug concentration level monitoring is warranted.https://theijpt.org/doi/pdf/10.9740/mhc.2022.06.214lithium toxicitybipolar disorderbariatric surgeryobesitymalabsorption |
| spellingShingle | Shahana Ayub, MD Sundas Saboor, MD Sadia Usmani, MD Sana Javed, MD Gauvain Kankeu Tonpouwo, MD Saeed Ahmed, MD Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case Mental Health Clinician lithium toxicity bipolar disorder bariatric surgery obesity malabsorption |
| title | Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case |
| title_full | Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case |
| title_fullStr | Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case |
| title_full_unstemmed | Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case |
| title_short | Lithium toxicity following Roux-en-Y gastric bypass: Mini review and illustrative case |
| title_sort | lithium toxicity following roux en y gastric bypass mini review and illustrative case |
| topic | lithium toxicity bipolar disorder bariatric surgery obesity malabsorption |
| url | https://theijpt.org/doi/pdf/10.9740/mhc.2022.06.214 |
| work_keys_str_mv | AT shahanaayubmd lithiumtoxicityfollowingrouxenygastricbypassminireviewandillustrativecase AT sundassaboormd lithiumtoxicityfollowingrouxenygastricbypassminireviewandillustrativecase AT sadiausmanimd lithiumtoxicityfollowingrouxenygastricbypassminireviewandillustrativecase AT sanajavedmd lithiumtoxicityfollowingrouxenygastricbypassminireviewandillustrativecase AT gauvainkankeutonpouwomd lithiumtoxicityfollowingrouxenygastricbypassminireviewandillustrativecase AT saeedahmedmd lithiumtoxicityfollowingrouxenygastricbypassminireviewandillustrativecase |