Clinical implications of aberrant PD-1 expression for acute leukemia prognosis

Clinical implications of aberrant PD-1 expression for acute leukemia prognosis

Abstract Background Acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) are the most common types of leukemia in adults with an overall poor prognosis. PD-1 alone or combined with other immune checkpoint blockade is a promising research direction for the treatment of acute leukemia (...

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Bibliographic Details
Main Authors: Yanjie Ruan, Jiyu Wang, Qiuye Zhang, Huiping Wang, Cong Li, Xuanxuan Xu, Zhimin Zhai
Format: Article
Language:English
Published: BMC 2023-09-01
Series:European Journal of Medical Research
Subjects:
PD-1
Acute lymphoma leukemia
Acute myeloid leukemia
CD4+ T lymphocytes
CD8+ T lymphocytes
Prognosis
Online Access:https://doi.org/10.1186/s40001-023-01352-8

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