Stratified Treatment of Heart Failure with preserved Ejection Fraction: rationale and design of the STADIA‐HFpEF trial

Stratified Treatment of Heart Failure with preserved Ejection Fraction: rationale and design of the STADIA‐HFpEF trial

Abstract Aims High myocardial stiffness in heart failure with preserved ejection fraction (HFpEF) is attributed to comorbidity‐induced structural and functional remodelling through inflammation and oxidative stress affecting coronary microvascular endothelial cells and cardiomyocytes, which augments...

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Bibliographic Details
Main Authors: Mariëlle Scheffer, Annet Driessen‐Waaijer, Nazha Hamdani, Jochem W.D. Landzaat, Nini H. Jonkman, Walter J. Paulus, Loek vanHeerebeek
Format: Article
Language:English
Published: Wiley 2020-12-01
Series:ESC Heart Failure
Subjects:
HFpEF
Heart failure
Cardiomyocyte
Dapagliflozin
Online Access:https://doi.org/10.1002/ehf2.13055

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