Genetic Architecture of Carcass and Meat Quality Traits in Montana Tropical® Composite Beef Cattle
The Montana Tropical® Composite is a recently developed beef cattle population that is rapidly expanding in Brazil and other tropical countries. This is mainly due to its improved meat quality and adaptation to tropical climate conditions compared to Zebu and Taurine cattle breeds, respectively. Thi...
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Frontiers Media S.A.
2020-02-01
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| Series: | Frontiers in Genetics |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fgene.2020.00123/full |
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| author | Laís Grigoletto Laís Grigoletto José B. S. Ferraz Hinayah R. Oliveira Joanir P. Eler Fernando O. Bussiman Barbara C. Abreu Silva Fernando Baldi Luiz F. Brito |
| author_facet | Laís Grigoletto Laís Grigoletto José B. S. Ferraz Hinayah R. Oliveira Joanir P. Eler Fernando O. Bussiman Barbara C. Abreu Silva Fernando Baldi Luiz F. Brito |
| author_sort | Laís Grigoletto |
| collection | DOAJ |
| description | The Montana Tropical® Composite is a recently developed beef cattle population that is rapidly expanding in Brazil and other tropical countries. This is mainly due to its improved meat quality and adaptation to tropical climate conditions compared to Zebu and Taurine cattle breeds, respectively. This study aimed to investigate the genetic architecture of ultrasound-based carcass and meat quality traits in Montana Tropical® Composite beef cattle. Therefore, we estimated variance components and genetic parameters and performed genome-wide association studies using the weighted single-step Genomic Best Linear Unbiased Prediction (GBLUP) approach. A pedigree dataset containing 28,480 animals was used, in which 1,436 were genotyped using a moderate-density Single Nucleotide Polymorphism panel (30K; 30,105 SNPs). A total of 9,358, 5,768, 7,996, and 1,972 phenotypic records for the traits Longissimus muscle area (LMA), backfat thickness (BFT), rump fat thickness (RFT), and for marbling score (MARB), respectively, were used for the analyses. Moderate to high heritability estimates were obtained and ranged from 0.16 ± 0.03 (RFT) to 0.33 ± 0.05 (MARB). A high genetic correlation was observed between BFT and RFT (0.97 ± 0.02), suggesting that a similar set of genes affects both traits. The most relevant genomic regions associated with LMA, BFT, RFT, and MARB were found on BTA10 (5.4–5.8 Mb), BTA27 (25.2–25.5 Mb), BTA18 (60.6–61.0 Mb), and BTA21 (14.8–15.4 Mb). Two overlapping genomic regions were identified for RFT and MARB (BTA13:47.9–48.1 Mb) and for BFT and RFT (BTA13:61.5–62.3 Mb). Candidate genes identified in this study, including PLAG1, LYN, WWOX, and PLAGL2, were previously reported to be associated with growth, stature, skeletal muscle growth, fat thickness, and fatty acid composition. Our results indicate that ultrasound-based carcass and meat quality traits in the Montana Tropical® Composite beef cattle are heritable, and therefore, can be improved through selective breeding. In addition, various novel and already known genomic regions related to these traits were identified, which contribute to a better understanding of the underlying genetic background of LMA, BFT, RFT, and MARB in the Montana Tropical Composite population. |
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| spelling | doaj.art-99c0ab69f83b4232b168bb63485a4e872022-12-21T19:55:45ZengFrontiers Media S.A.Frontiers in Genetics1664-80212020-02-011110.3389/fgene.2020.00123508281Genetic Architecture of Carcass and Meat Quality Traits in Montana Tropical® Composite Beef CattleLaís Grigoletto0Laís Grigoletto1José B. S. Ferraz2Hinayah R. Oliveira3Joanir P. Eler4Fernando O. Bussiman5Barbara C. Abreu Silva6Fernando Baldi7Luiz F. Brito8Department of Animal Sciences, College of Animal Sciences and Food Engineering, University of São Paulo, Pirassununga, BrazilDepartment of Animal Sciences, Purdue University, West Lafayette, IN, United StatesDepartment of Animal Sciences, College of Animal Sciences and Food Engineering, University of São Paulo, Pirassununga, BrazilDepartment of Animal Sciences, Purdue University, West Lafayette, IN, United StatesDepartment of Animal Sciences, College of Animal Sciences and Food Engineering, University of São Paulo, Pirassununga, BrazilDepartment of Animal Sciences, College of Animal Sciences and Food Engineering, University of São Paulo, Pirassununga, BrazilDepartment of Animal Sciences, College of Animal Sciences and Food Engineering, University of São Paulo, Pirassununga, BrazilDepartment of Animal Sciences, College of Agricultural and Veterinary Sciences, São Paulo State University, Jaboticabal, BrazilDepartment of Animal Sciences, Purdue University, West Lafayette, IN, United StatesThe Montana Tropical® Composite is a recently developed beef cattle population that is rapidly expanding in Brazil and other tropical countries. This is mainly due to its improved meat quality and adaptation to tropical climate conditions compared to Zebu and Taurine cattle breeds, respectively. This study aimed to investigate the genetic architecture of ultrasound-based carcass and meat quality traits in Montana Tropical® Composite beef cattle. Therefore, we estimated variance components and genetic parameters and performed genome-wide association studies using the weighted single-step Genomic Best Linear Unbiased Prediction (GBLUP) approach. A pedigree dataset containing 28,480 animals was used, in which 1,436 were genotyped using a moderate-density Single Nucleotide Polymorphism panel (30K; 30,105 SNPs). A total of 9,358, 5,768, 7,996, and 1,972 phenotypic records for the traits Longissimus muscle area (LMA), backfat thickness (BFT), rump fat thickness (RFT), and for marbling score (MARB), respectively, were used for the analyses. Moderate to high heritability estimates were obtained and ranged from 0.16 ± 0.03 (RFT) to 0.33 ± 0.05 (MARB). A high genetic correlation was observed between BFT and RFT (0.97 ± 0.02), suggesting that a similar set of genes affects both traits. The most relevant genomic regions associated with LMA, BFT, RFT, and MARB were found on BTA10 (5.4–5.8 Mb), BTA27 (25.2–25.5 Mb), BTA18 (60.6–61.0 Mb), and BTA21 (14.8–15.4 Mb). Two overlapping genomic regions were identified for RFT and MARB (BTA13:47.9–48.1 Mb) and for BFT and RFT (BTA13:61.5–62.3 Mb). Candidate genes identified in this study, including PLAG1, LYN, WWOX, and PLAGL2, were previously reported to be associated with growth, stature, skeletal muscle growth, fat thickness, and fatty acid composition. Our results indicate that ultrasound-based carcass and meat quality traits in the Montana Tropical® Composite beef cattle are heritable, and therefore, can be improved through selective breeding. In addition, various novel and already known genomic regions related to these traits were identified, which contribute to a better understanding of the underlying genetic background of LMA, BFT, RFT, and MARB in the Montana Tropical Composite population.https://www.frontiersin.org/article/10.3389/fgene.2020.00123/fullcandidate genescomposite cattlecrossbreedinggenomic regionssingle-step Genome-Wide Association Studies (ssGWAS)Genomic Best Linear Unbiased Prediction (GBLUP) |
| spellingShingle | Laís Grigoletto Laís Grigoletto José B. S. Ferraz Hinayah R. Oliveira Joanir P. Eler Fernando O. Bussiman Barbara C. Abreu Silva Fernando Baldi Luiz F. Brito Genetic Architecture of Carcass and Meat Quality Traits in Montana Tropical® Composite Beef Cattle Frontiers in Genetics candidate genes composite cattle crossbreeding genomic regions single-step Genome-Wide Association Studies (ssGWAS) Genomic Best Linear Unbiased Prediction (GBLUP) |
| title | Genetic Architecture of Carcass and Meat Quality Traits in Montana Tropical® Composite Beef Cattle |
| title_full | Genetic Architecture of Carcass and Meat Quality Traits in Montana Tropical® Composite Beef Cattle |
| title_fullStr | Genetic Architecture of Carcass and Meat Quality Traits in Montana Tropical® Composite Beef Cattle |
| title_full_unstemmed | Genetic Architecture of Carcass and Meat Quality Traits in Montana Tropical® Composite Beef Cattle |
| title_short | Genetic Architecture of Carcass and Meat Quality Traits in Montana Tropical® Composite Beef Cattle |
| title_sort | genetic architecture of carcass and meat quality traits in montana tropical r composite beef cattle |
| topic | candidate genes composite cattle crossbreeding genomic regions single-step Genome-Wide Association Studies (ssGWAS) Genomic Best Linear Unbiased Prediction (GBLUP) |
| url | https://www.frontiersin.org/article/10.3389/fgene.2020.00123/full |
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