Renin-angiotensin system inhibitors combined with cisplatin exacerbate cisplatin-induced nephrotoxicity in mice

Renin-angiotensin system inhibitors combined with cisplatin exacerbate cisplatin-induced nephrotoxicity in mice

Introduction: We previously reported that the concomitant use of enalapril and telmisartan exacerbates the risk of cisplatin (CDDP)-induced acute renal dysfunction compared to other antihypertensive drugs in mice. Thus, in the current study, we investigated the risk of developing chronic kidney dise...

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Bibliographic Details
Main Authors: Takumi Tsuji, Atsuki Hosoda, Yuuki Toriyama, Yuya Yoshida, Takeyuki Kohno
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Translational Oncology
Subjects:
Cisplatin
Renin-angiotensin system inhibitor
Nephrotoxicity
Fibrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523322000316

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