Bone Mineral Density Assessment by Quantitative Computed Tomography in Glucocorticoid-Treated Boys With Duchenne Muscular Dystrophy: A Linear Mixed-Effects Modeling Approach

Bone Mineral Density Assessment by Quantitative Computed Tomography in Glucocorticoid-Treated Boys With Duchenne Muscular Dystrophy: A Linear Mixed-Effects Modeling Approach

ObjectiveBoys with Duchenne muscular dystrophy (DMD) are at risk of bone damage and low bone mineral density (BMD). The aim of the study is to examine lumbar BMD values measured by QCT and identify the factors associated with BMD loss using a multilevel mixed-effects model.MethodsLumbar BMD was eval...

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Bibliographic Details
Main Authors: Chuan Liu, Dan-Dan Yang, Lu Zhang, Xian-Gao Lei, Feng-Lin Jia, Yi Liao, Xi-Jian Chen, Gang Ning, Wen Luo, Hai-Bo Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Endocrinology
Subjects:
Duchenne muscular dystrophy
osteoporosis
bone mineral density
glucocorticoids
quantitative computed tomography
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.860413/full

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