Carboplatin, pemetrexed, and pembrolizumab was effective for primary salivary gland‐type lung adenocarcinoma diagnosed due to esophageal stricture: A case report
Abstract Primary salivary gland‐type tumors of the lung are rare, accounting for <1% of all lung tumors. There are few reports on chemotherapy for the treatment of primary salivary gland‐type tumors of the lung. The patient in this report was a 71‐year‐old woman who presented with a chief complai...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-09-01
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| Series: | Thoracic Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/1759-7714.14100 |
| _version_ | 1819115658129965056 |
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| author | Keita Kawakado Tomoki Tamura Masamoto Nakanishi Go Makimoto Yumiko Sato Shoichi Kuyama |
| author_facet | Keita Kawakado Tomoki Tamura Masamoto Nakanishi Go Makimoto Yumiko Sato Shoichi Kuyama |
| author_sort | Keita Kawakado |
| collection | DOAJ |
| description | Abstract Primary salivary gland‐type tumors of the lung are rare, accounting for <1% of all lung tumors. There are few reports on chemotherapy for the treatment of primary salivary gland‐type tumors of the lung. The patient in this report was a 71‐year‐old woman who presented with a chief complaint of dysphagia. Upper gastrointestinal endoscopy revealed an esophageal stricture, but biopsy showed no malignancy. Chest computed tomography (CT) showed carcinomatous lymphangiomatosis and a nodule in the right lung. Bronchoscopy showed a rough mucous membrane of the central bronchi, while biopsy showed adenocarcinoma. The patient was diagnosed with bronchogenic adenocarcinoma and received carboplatin, pemetrexed, and pembrolizumab, which alleviated the esophageal stricture and cancerous lymphangiopathy. However, the adenocarcinoma progressed, and she subsequently received several rounds of chemotherapy. One year after diagnosis, the patient died, and pathological autopsy revealed primary salivary gland‐type tumors of the lung. |
| first_indexed | 2024-12-22T05:04:41Z |
| format | Article |
| id | doaj.art-99c3b1deb8f54113a118c500f217d317 |
| institution | Directory Open Access Journal |
| issn | 1759-7706 1759-7714 |
| language | English |
| last_indexed | 2024-12-22T05:04:41Z |
| publishDate | 2021-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Thoracic Cancer |
| spelling | doaj.art-99c3b1deb8f54113a118c500f217d3172022-12-21T18:38:08ZengWileyThoracic Cancer1759-77061759-77142021-09-0112182513251610.1111/1759-7714.14100Carboplatin, pemetrexed, and pembrolizumab was effective for primary salivary gland‐type lung adenocarcinoma diagnosed due to esophageal stricture: A case reportKeita Kawakado0Tomoki Tamura1Masamoto Nakanishi2Go Makimoto3Yumiko Sato4Shoichi Kuyama5Department of Respiratory Medicine National Hospital Organization Iwakuni Clinical Center Iawkuni‐City JapanDepartment of Respiratory Medicine National Hospital Organization Iwakuni Clinical Center Iawkuni‐City JapanDepartment of Respiratory Medicine National Hospital Organization Iwakuni Clinical Center Iawkuni‐City JapanDepartment of Respiratory Medicine National Hospital Organization Iwakuni Clinical Center Iawkuni‐City JapanDepartment of Pathology National Hospital Organization Iwakuni Clinical Center Iawkuni‐City JapanDepartment of Respiratory Medicine National Hospital Organization Iwakuni Clinical Center Iawkuni‐City JapanAbstract Primary salivary gland‐type tumors of the lung are rare, accounting for <1% of all lung tumors. There are few reports on chemotherapy for the treatment of primary salivary gland‐type tumors of the lung. The patient in this report was a 71‐year‐old woman who presented with a chief complaint of dysphagia. Upper gastrointestinal endoscopy revealed an esophageal stricture, but biopsy showed no malignancy. Chest computed tomography (CT) showed carcinomatous lymphangiomatosis and a nodule in the right lung. Bronchoscopy showed a rough mucous membrane of the central bronchi, while biopsy showed adenocarcinoma. The patient was diagnosed with bronchogenic adenocarcinoma and received carboplatin, pemetrexed, and pembrolizumab, which alleviated the esophageal stricture and cancerous lymphangiopathy. However, the adenocarcinoma progressed, and she subsequently received several rounds of chemotherapy. One year after diagnosis, the patient died, and pathological autopsy revealed primary salivary gland‐type tumors of the lung.https://doi.org/10.1111/1759-7714.14100carboplatincase reportpembrolizumabpemetrexedprimary salivary gland‐type tumor of the lung |
| spellingShingle | Keita Kawakado Tomoki Tamura Masamoto Nakanishi Go Makimoto Yumiko Sato Shoichi Kuyama Carboplatin, pemetrexed, and pembrolizumab was effective for primary salivary gland‐type lung adenocarcinoma diagnosed due to esophageal stricture: A case report Thoracic Cancer carboplatin case report pembrolizumab pemetrexed primary salivary gland‐type tumor of the lung |
| title | Carboplatin, pemetrexed, and pembrolizumab was effective for primary salivary gland‐type lung adenocarcinoma diagnosed due to esophageal stricture: A case report |
| title_full | Carboplatin, pemetrexed, and pembrolizumab was effective for primary salivary gland‐type lung adenocarcinoma diagnosed due to esophageal stricture: A case report |
| title_fullStr | Carboplatin, pemetrexed, and pembrolizumab was effective for primary salivary gland‐type lung adenocarcinoma diagnosed due to esophageal stricture: A case report |
| title_full_unstemmed | Carboplatin, pemetrexed, and pembrolizumab was effective for primary salivary gland‐type lung adenocarcinoma diagnosed due to esophageal stricture: A case report |
| title_short | Carboplatin, pemetrexed, and pembrolizumab was effective for primary salivary gland‐type lung adenocarcinoma diagnosed due to esophageal stricture: A case report |
| title_sort | carboplatin pemetrexed and pembrolizumab was effective for primary salivary gland type lung adenocarcinoma diagnosed due to esophageal stricture a case report |
| topic | carboplatin case report pembrolizumab pemetrexed primary salivary gland‐type tumor of the lung |
| url | https://doi.org/10.1111/1759-7714.14100 |
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