Evidence of a genetically driven metabolomic signature in actively inflamed Crohn’s disease

Evidence of a genetically driven metabolomic signature in actively inflamed Crohn’s disease

Abstract Crohn’s disease (CD) is characterised by chronic inflammation. We aimed to identify a relationship between plasma inflammatory metabolomic signature and genomic data in CD using blood plasma metabolic profiles. Proton NMR spectroscopy were achieved for 228 paediatric CD patients. Regression...

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Bibliographic Details
Main Authors: Enrico Mossotto, Joanna Boberska, James J. Ashton, Imogen S. Stafford, Guo Cheng, Jonathan Baker, Florina Borca, Hang T. T. Phan, Tracy F. Coelho, R. Mark Beattie, Sandrine P. Claus, Sarah Ennis
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-18178-9

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