New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report

Ischemic stroke is a complex multifactorial disorder. Anticoagulation is a growing research area, with the main goal of preventing systemic embolization and stroke. We report the case of a 41-year-old woman with antiphospholipid syndrome who was unsuccessfully treated with Dabigatran, a new oral ant...

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Main Authors: Francesca Antonia Arcadi, Simona Portaro, Roberto Giorgianni, Antonino Naro, Carmela Casella, Carmelo Genovese, Silvia Marino, Rocco Salvatore Calabrò
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Medicina
Subjects:
Online Access:http://www.mdpi.com/1010-660X/55/3/71
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author Francesca Antonia Arcadi
Simona Portaro
Roberto Giorgianni
Antonino Naro
Carmela Casella
Carmelo Genovese
Silvia Marino
Rocco Salvatore Calabrò
author_facet Francesca Antonia Arcadi
Simona Portaro
Roberto Giorgianni
Antonino Naro
Carmela Casella
Carmelo Genovese
Silvia Marino
Rocco Salvatore Calabrò
author_sort Francesca Antonia Arcadi
collection DOAJ
description Ischemic stroke is a complex multifactorial disorder. Anticoagulation is a growing research area, with the main goal of preventing systemic embolization and stroke. We report the case of a 41-year-old woman with antiphospholipid syndrome who was unsuccessfully treated with Dabigatran, a new oral anticoagulant, as she developed a major stroke involving the right carotid artery, due to deep venous thrombosis with pulmonary embolism. We therefore suggest a closer monitoring of the safety and efficacy of dabigatran. Moreover, in the presence of multifactorial causes of pro-coagulation, we believe that warfarin should remain the mainstay of oral anticoagulation.
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spelling doaj.art-99c46dec3233445ea521523887027f932023-09-02T05:31:28ZengMDPI AGMedicina1010-660X2019-03-015537110.3390/medicina55030071medicina55030071New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case ReportFrancesca Antonia Arcadi0Simona Portaro1Roberto Giorgianni2Antonino Naro3Carmela Casella4Carmelo Genovese5Silvia Marino6Rocco Salvatore Calabrò7IRCCS Centro Neurolesi “Bonino-Pulejo”, 98123 Messina, ItalyIRCCS Centro Neurolesi “Bonino-Pulejo”, 98123 Messina, ItalyIRCCS Centro Neurolesi “Bonino-Pulejo”, 98123 Messina, ItalyIRCCS Centro Neurolesi “Bonino-Pulejo”, 98123 Messina, ItalyStroke Unit, Policlinico Universitario, 98123 Messina, ItalyGenovese Laboratory Medicine and Pathology, 98050 Barcellona PG, ItalyIRCCS Centro Neurolesi “Bonino-Pulejo”, 98123 Messina, ItalyIRCCS Centro Neurolesi “Bonino-Pulejo”, 98123 Messina, ItalyIschemic stroke is a complex multifactorial disorder. Anticoagulation is a growing research area, with the main goal of preventing systemic embolization and stroke. We report the case of a 41-year-old woman with antiphospholipid syndrome who was unsuccessfully treated with Dabigatran, a new oral anticoagulant, as she developed a major stroke involving the right carotid artery, due to deep venous thrombosis with pulmonary embolism. We therefore suggest a closer monitoring of the safety and efficacy of dabigatran. Moreover, in the presence of multifactorial causes of pro-coagulation, we believe that warfarin should remain the mainstay of oral anticoagulation.http://www.mdpi.com/1010-660X/55/3/71dabigatranwarfarinischemic strokeanticoagulants
spellingShingle Francesca Antonia Arcadi
Simona Portaro
Roberto Giorgianni
Antonino Naro
Carmela Casella
Carmelo Genovese
Silvia Marino
Rocco Salvatore Calabrò
New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report
Medicina
dabigatran
warfarin
ischemic stroke
anticoagulants
title New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report
title_full New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report
title_fullStr New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report
title_full_unstemmed New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report
title_short New versus Old Oral Anticoagulants: How Can We Set the Scale Needle? Considerations on a Case Report
title_sort new versus old oral anticoagulants how can we set the scale needle considerations on a case report
topic dabigatran
warfarin
ischemic stroke
anticoagulants
url http://www.mdpi.com/1010-660X/55/3/71
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