5-Aminolevulinic Acid-Mediated Photodynamic Therapy Potentiates the Effectiveness of Doxorubicin in Ewing Sarcomas

5-Aminolevulinic Acid-Mediated Photodynamic Therapy Potentiates the Effectiveness of Doxorubicin in Ewing Sarcomas

Ewing sarcomas (ES) are aggressive primary bone tumors that require radical therapy. Promising low toxicity, 5-aminolevulinic acid (5-ALA)-mediated photodynamic therapy (PDT) could enhance the effectiveness of conventional treatment modalities (e.g., doxorubicin (DOX)), improving, thus, the anti-tum...

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Bibliographic Details
Main Authors: Lea Marocco, Felix Umrath, Saskia Sachsenmaier, Robert Rabiner, Nikolaus Wülker, Marina Danalache
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomedicines
Subjects:
Ewing sarcoma
photodynamic therapy
doxorubicin
combination therapy
cytoskeleton
atomic force microscopy
Online Access:https://www.mdpi.com/2227-9059/10/11/2900

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