Elevated brain-derived cell-free DNA among patients with first psychotic episode – a proof-of-concept study

Elevated brain-derived cell-free DNA among patients with first psychotic episode – a proof-of-concept study

Schizophrenia is a common, severe, and debilitating psychiatric disorder. Despite extensive research there is as yet no biological marker that can aid in its diagnosis and course prediction. This precludes early detection and intervention. Imaging studies suggest brain volume loss around the onset a...

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Bibliographic Details
Main Authors: Asael Lubotzky, Ilana Pelov, Ronen Teplitz, Daniel Neiman, Adama Smadja, Hai Zemmour, Sheina Piyanzin, Bracha-Lea Ochana, Kirsty L Spalding, Benjamin Glaser, Ruth Shemer, Yuval Dor, Yoav Kohn
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-06-01
Series:eLife
Subjects:
DNA methylation
cfDNA
psychosis
liquid biopsy
epigenetics
biomarker
Online Access:https://elifesciences.org/articles/76391

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