Effect of dietary taurine supplementation on metabolome variation in plasma of Nile tilapia
Taurine has been considered as an essential nutrient for many aquaculture species. While dietary taurine supplementation is highly recommended, novelty studies on taurine metabolism in fish are needed. The present study aimed to provide insight into the molecular mechanisms involved in multiple meta...
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| Format: | Article |
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Elsevier
2021-03-01
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| Series: | Animal |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1751731120301695 |
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| author | G.P. Shen Z.N. Ding T. Dai J.H. Feng J.Y. Dong F. Xia J.J. Xu J.D. Ye |
| author_facet | G.P. Shen Z.N. Ding T. Dai J.H. Feng J.Y. Dong F. Xia J.J. Xu J.D. Ye |
| author_sort | G.P. Shen |
| collection | DOAJ |
| description | Taurine has been considered as an essential nutrient for many aquaculture species. While dietary taurine supplementation is highly recommended, novelty studies on taurine metabolism in fish are needed. The present study aimed to provide insight into the molecular mechanisms involved in multiple metabolome changes in Nile tilapia (Oreochromis niloticus) by studying plasma metabolic profile changes in response to graded levels of dietary taurine supplementation. The analysis used proton nuclear magnetic resonance-based metabolomics. Four groups of tilapias were fed with four diets supplemented with 0.0, 0.4, 0.8 and 1.2% taurine for 84 days. Fish plasma was sampled at multiple time points to provide an accurate snapshot of specific metabolic profiles during growth. Under the effect of taurine supplementation, 21 and 12 metabolites in tilapia plasma shown significant changes in terms of time-dependence and diet-dependence, respectively. These metabolic changes in tilapia plasma were mainly associated with energy and amino acid metabolism, lipids, nucleotides and protein metabolism. The results indicate that 0.8% taurine supplementation could significantly improve the carbohydrate synthesis, protein digestion and absorption, and fat deposition of tilapia and thereby promoted growth and development of tilapia. |
| first_indexed | 2024-12-14T17:24:50Z |
| format | Article |
| id | doaj.art-99c655ce25854d61b22447e5766dc438 |
| institution | Directory Open Access Journal |
| issn | 1751-7311 |
| language | English |
| last_indexed | 2024-12-14T17:24:50Z |
| publishDate | 2021-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Animal |
| spelling | doaj.art-99c655ce25854d61b22447e5766dc4382022-12-21T22:53:15ZengElsevierAnimal1751-73112021-03-01153100167Effect of dietary taurine supplementation on metabolome variation in plasma of Nile tilapiaG.P. Shen0Z.N. Ding1T. Dai2J.H. Feng3J.Y. Dong4F. Xia5J.J. Xu6J.D. Ye7Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen 361005, China; Corresponding author.Department of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen 361005, ChinaDepartment of Plastic Surgery, Affiliated Third Hospital, Henan University of Science and Technology, Luoyang 471003, ChinaDepartment of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen 361005, ChinaDepartment of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen 361005, ChinaDepartment of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen 361005, ChinaDepartment of Electronic Science, Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance, Xiamen University, Xiamen 361005, ChinaFisheries College, Xiamen Key Laboratory for Feed Quality Testing and Safety Evaluation, Jimei University, Xiamen 361021, ChinaTaurine has been considered as an essential nutrient for many aquaculture species. While dietary taurine supplementation is highly recommended, novelty studies on taurine metabolism in fish are needed. The present study aimed to provide insight into the molecular mechanisms involved in multiple metabolome changes in Nile tilapia (Oreochromis niloticus) by studying plasma metabolic profile changes in response to graded levels of dietary taurine supplementation. The analysis used proton nuclear magnetic resonance-based metabolomics. Four groups of tilapias were fed with four diets supplemented with 0.0, 0.4, 0.8 and 1.2% taurine for 84 days. Fish plasma was sampled at multiple time points to provide an accurate snapshot of specific metabolic profiles during growth. Under the effect of taurine supplementation, 21 and 12 metabolites in tilapia plasma shown significant changes in terms of time-dependence and diet-dependence, respectively. These metabolic changes in tilapia plasma were mainly associated with energy and amino acid metabolism, lipids, nucleotides and protein metabolism. The results indicate that 0.8% taurine supplementation could significantly improve the carbohydrate synthesis, protein digestion and absorption, and fat deposition of tilapia and thereby promoted growth and development of tilapia.http://www.sciencedirect.com/science/article/pii/S1751731120301695MetabolomicsNile tilapiaNuclear magnetic resonancePlasma metabolicTaurine |
| spellingShingle | G.P. Shen Z.N. Ding T. Dai J.H. Feng J.Y. Dong F. Xia J.J. Xu J.D. Ye Effect of dietary taurine supplementation on metabolome variation in plasma of Nile tilapia Animal Metabolomics Nile tilapia Nuclear magnetic resonance Plasma metabolic Taurine |
| title | Effect of dietary taurine supplementation on metabolome variation in plasma of Nile tilapia |
| title_full | Effect of dietary taurine supplementation on metabolome variation in plasma of Nile tilapia |
| title_fullStr | Effect of dietary taurine supplementation on metabolome variation in plasma of Nile tilapia |
| title_full_unstemmed | Effect of dietary taurine supplementation on metabolome variation in plasma of Nile tilapia |
| title_short | Effect of dietary taurine supplementation on metabolome variation in plasma of Nile tilapia |
| title_sort | effect of dietary taurine supplementation on metabolome variation in plasma of nile tilapia |
| topic | Metabolomics Nile tilapia Nuclear magnetic resonance Plasma metabolic Taurine |
| url | http://www.sciencedirect.com/science/article/pii/S1751731120301695 |
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