More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction

More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction

Our understanding of how capillary blood flow and oxygen distribute across cortical layers to meet the local metabolic demand is incomplete. We addressed this question by using two-photon imaging of resting-state microvascular oxygen partial pressure (PO2) and flow in the whisker barrel cortex in aw...

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Bibliographic Details
Main Authors:	Baoqiang Li, Tatiana V Esipova, Ikbal Sencan, Kıvılcım Kılıç, Buyin Fu, Michele Desjardins, Mohammad Moeini, Sreekanth Kura, Mohammad A Yaseen, Frederic Lesage, Leif Østergaard, Anna Devor, David A Boas, Sergei A Vinogradov, Sava Sakadžić
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2019-07-01
Series:	eLife
Subjects:	cerebral cortex capillary oxygenation capillary blood flow two-photon phosphorescence lifetime microscopy partial pressure of oxygen
Online Access:	https://elifesciences.org/articles/42299

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