Timing of additional neoadjuvant chemotherapy in patients with locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy and total mesorectal excision

Abstract Background In locally advanced rectal cancer (LARC), the optimal sequence of neoadjuvant chemotherapy in relation to neoadjuvant chemoradiotherapy and before total mesorectal excision is unknown. Methods A total of 426 LARC patients, treated with neoadjuvant chemoradiotherapy followed by to...

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Bibliographic Details
Main Authors: Fang He, Mo Chen, Yan-ping Liu, Jiachun Sun, Jian Zheng
Format: Article
Language:English
Published: Springer 2022-10-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-022-00572-4