Inflammation induced insulin resistance is associated with DNA methylation changes in vascular endothelial cells

Vascular insulin resistance manifests in decreased production of nitric oxide subsequently leading to vasoconstriction and atherosclerosis. Inflammatory molecules such as IL-6 are known to induce insulin resistance in vascular endothelial cells. Epigenetic mechanisms including promoter DNA methylati...

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Bibliographic Details
Main Authors: Aswath Balakrishnan, Kapaettu Satyamoorthy, Manjunath B. Joshi
Format: Article
Language:English
Published: Science Planet Inc. 2017-10-01
Series:Canadian Journal of Biotechnology
Online Access:https://www.canadianjbiotech.com/CAN_J_BIOTECH/Archives/v1/Special Issue/cjb.2017-a90.pdf