The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region
Purpose: to study the diversity of the clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region.Methods: We conducted an epidemiological study of hereditary ophthalmopathology population of the Rostov region. the popula- tion surveyed 12...
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| Format: | Article |
| Language: | Russian |
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Ophthalmology Publishing Group
2014-07-01
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| Series: | Oftalʹmologiâ |
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| Online Access: | https://www.ophthalmojournal.com/opht/article/view/166 |
| _version_ | 1797875531632345088 |
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| author | O. L. Kireeva O. V. Chlebnikova S. S. Amelina G. I. Elchinova R. A. Zinchenko V. V. Kadsjyshev E. K. Ginter |
| author_facet | O. L. Kireeva O. V. Chlebnikova S. S. Amelina G. I. Elchinova R. A. Zinchenko V. V. Kadsjyshev E. K. Ginter |
| author_sort | O. L. Kireeva |
| collection | DOAJ |
| description | Purpose: to study the diversity of the clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region.Methods: We conducted an epidemiological study of hereditary ophthalmopathology population of the Rostov region. the popula- tion surveyed 12 districts of the region — 497460 people, including 97345 children (0-18 years). Regardless of age for the selection of patients used the original protocol of genetic-epidemiological studies, developed over 30 years ago, in Genetic Epidemiology Labora- tory Medical Genetic Research Center.Results: In the group of the child population identified 84 patients from 72 families. the most commonly diagnosed congenital cataract various forms (36.1%), congenital horizontal nystagmus (18.0%), monogenic defects eyes (15.6%), congenital ptosis (15.6%), hereditary retinal dystrophy (9, 6%). the overall prevalence of hereditary eye diseases among the adult population was 2.42±0.25, children 8.63±0.94 to 10,000 people.Conclusion: Conducting genetic epidemiology studies will improve eye health and medical genetic care. |
| first_indexed | 2024-04-10T01:49:00Z |
| format | Article |
| id | doaj.art-99d86c97413a4bda837effa2f75ea9b3 |
| institution | Directory Open Access Journal |
| issn | 1816-5095 2500-0845 |
| language | Russian |
| last_indexed | 2024-04-10T01:49:00Z |
| publishDate | 2014-07-01 |
| publisher | Ophthalmology Publishing Group |
| record_format | Article |
| series | Oftalʹmologiâ |
| spelling | doaj.art-99d86c97413a4bda837effa2f75ea9b32023-03-13T09:08:35ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452014-07-019481310.18008/1816-5095-2012-4-8-13166The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov regionO. L. Kireeva0O. V. Chlebnikova1S. S. Amelina2G. I. Elchinova3R. A. Zinchenko4V. V. Kadsjyshev5E. K. Ginter6Медико-генетический научный центр Российской академии медицинских наук, МоскваМедико-генетический научный центр Российской академии медицинских наук, МоскваРостовская областная клиническая больница, Ростов-на-ДонуМедико-генетический научный центр Российской академии медицинских наук, МоскваМедико-генетический научный центр Российской академии медицинских наук, МоскваМедико-генетический научный центр Российской академии медицинских наук, МоскваМедико-генетический научный центр Российской академии медицинских наук, МоскваPurpose: to study the diversity of the clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region.Methods: We conducted an epidemiological study of hereditary ophthalmopathology population of the Rostov region. the popula- tion surveyed 12 districts of the region — 497460 people, including 97345 children (0-18 years). Regardless of age for the selection of patients used the original protocol of genetic-epidemiological studies, developed over 30 years ago, in Genetic Epidemiology Labora- tory Medical Genetic Research Center.Results: In the group of the child population identified 84 patients from 72 families. the most commonly diagnosed congenital cataract various forms (36.1%), congenital horizontal nystagmus (18.0%), monogenic defects eyes (15.6%), congenital ptosis (15.6%), hereditary retinal dystrophy (9, 6%). the overall prevalence of hereditary eye diseases among the adult population was 2.42±0.25, children 8.63±0.94 to 10,000 people.Conclusion: Conducting genetic epidemiology studies will improve eye health and medical genetic care.https://www.ophthalmojournal.com/opht/article/view/166наследственная офтальмопатологияраспространенностьклинический полиморфизм abstract |
| spellingShingle | O. L. Kireeva O. V. Chlebnikova S. S. Amelina G. I. Elchinova R. A. Zinchenko V. V. Kadsjyshev E. K. Ginter The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region Oftalʹmologiâ наследственная офтальмопатология распространенность клинический полиморфизм abstract |
| title | The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region |
| title_full | The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region |
| title_fullStr | The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region |
| title_full_unstemmed | The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region |
| title_short | The clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the Rostov region |
| title_sort | clinical spectrum and prevalence of hereditary ophthalmopathology child population in 12 districts of the rostov region |
| topic | наследственная офтальмопатология распространенность клинический полиморфизм abstract |
| url | https://www.ophthalmojournal.com/opht/article/view/166 |
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