Rapid species identification of pathogenic bacteria from a minute quantity exploiting three-dimensional quantitative phase imaging and artificial neural network

Label-free rapid deep-learning-based identification of bacterial species that classifies 3D refractive index tomograms into the species.

Bibliographic Details
Main Authors: Geon Kim, Daewoong Ahn, Minhee Kang, Jinho Park, DongHun Ryu, YoungJu Jo, Jinyeop Song, Jea Sung Ryu, Gunho Choi, Hyun Jung Chung, Kyuseok Kim, Doo Ryeon Chung, In Young Yoo, Hee Jae Huh, Hyun-seok Min, Nam Yong Lee, YongKeun Park
Format: Article
Language:English
Published: Nature Publishing Group 2022-06-01
Series:Light: Science & Applications
Online Access:https://doi.org/10.1038/s41377-022-00881-x
_version_ 1811334573850624000
author Geon Kim
Daewoong Ahn
Minhee Kang
Jinho Park
DongHun Ryu
YoungJu Jo
Jinyeop Song
Jea Sung Ryu
Gunho Choi
Hyun Jung Chung
Kyuseok Kim
Doo Ryeon Chung
In Young Yoo
Hee Jae Huh
Hyun-seok Min
Nam Yong Lee
YongKeun Park
author_facet Geon Kim
Daewoong Ahn
Minhee Kang
Jinho Park
DongHun Ryu
YoungJu Jo
Jinyeop Song
Jea Sung Ryu
Gunho Choi
Hyun Jung Chung
Kyuseok Kim
Doo Ryeon Chung
In Young Yoo
Hee Jae Huh
Hyun-seok Min
Nam Yong Lee
YongKeun Park
author_sort Geon Kim
collection DOAJ
description Label-free rapid deep-learning-based identification of bacterial species that classifies 3D refractive index tomograms into the species.
first_indexed 2024-04-13T17:10:14Z
format Article
id doaj.art-99d95847005f492f887e1aab6140e65d
institution Directory Open Access Journal
issn 2047-7538
language English
last_indexed 2024-04-13T17:10:14Z
publishDate 2022-06-01
publisher Nature Publishing Group
record_format Article
series Light: Science & Applications
spelling doaj.art-99d95847005f492f887e1aab6140e65d2022-12-22T02:38:18ZengNature Publishing GroupLight: Science & Applications2047-75382022-06-0111111210.1038/s41377-022-00881-xRapid species identification of pathogenic bacteria from a minute quantity exploiting three-dimensional quantitative phase imaging and artificial neural networkGeon Kim0Daewoong Ahn1Minhee Kang2Jinho Park3DongHun Ryu4YoungJu Jo5Jinyeop Song6Jea Sung Ryu7Gunho Choi8Hyun Jung Chung9Kyuseok Kim10Doo Ryeon Chung11In Young Yoo12Hee Jae Huh13Hyun-seok Min14Nam Yong Lee15YongKeun Park16Department of Physics, Korea Advanced Institute of Science and TechnologyTomocube Inc.Smart Healthcare & Device Research Center, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Physics, Korea Advanced Institute of Science and TechnologyDepartment of Physics, Korea Advanced Institute of Science and TechnologyDepartment of Physics, Korea Advanced Institute of Science and TechnologyDepartment of Physics, Korea Advanced Institute of Science and TechnologyGraduate School of Nanoscience and Technology, Korea Advanced Institute of Science and TechnologyTomocube Inc.Graduate School of Nanoscience and Technology, Korea Advanced Institute of Science and TechnologyDepartment of Emergency Medicine, Bundang CHA HospitalDivision of Infectious Diseases, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Laboratory Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of KoreaDepartment of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of MedicineTomocube Inc.Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of MedicineDepartment of Physics, Korea Advanced Institute of Science and TechnologyLabel-free rapid deep-learning-based identification of bacterial species that classifies 3D refractive index tomograms into the species.https://doi.org/10.1038/s41377-022-00881-x
spellingShingle Geon Kim
Daewoong Ahn
Minhee Kang
Jinho Park
DongHun Ryu
YoungJu Jo
Jinyeop Song
Jea Sung Ryu
Gunho Choi
Hyun Jung Chung
Kyuseok Kim
Doo Ryeon Chung
In Young Yoo
Hee Jae Huh
Hyun-seok Min
Nam Yong Lee
YongKeun Park
Rapid species identification of pathogenic bacteria from a minute quantity exploiting three-dimensional quantitative phase imaging and artificial neural network
Light: Science & Applications
title Rapid species identification of pathogenic bacteria from a minute quantity exploiting three-dimensional quantitative phase imaging and artificial neural network
title_full Rapid species identification of pathogenic bacteria from a minute quantity exploiting three-dimensional quantitative phase imaging and artificial neural network
title_fullStr Rapid species identification of pathogenic bacteria from a minute quantity exploiting three-dimensional quantitative phase imaging and artificial neural network
title_full_unstemmed Rapid species identification of pathogenic bacteria from a minute quantity exploiting three-dimensional quantitative phase imaging and artificial neural network
title_short Rapid species identification of pathogenic bacteria from a minute quantity exploiting three-dimensional quantitative phase imaging and artificial neural network
title_sort rapid species identification of pathogenic bacteria from a minute quantity exploiting three dimensional quantitative phase imaging and artificial neural network
url https://doi.org/10.1038/s41377-022-00881-x
work_keys_str_mv AT geonkim rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT daewoongahn rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT minheekang rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT jinhopark rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT donghunryu rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT youngjujo rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT jinyeopsong rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT jeasungryu rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT gunhochoi rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT hyunjungchung rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT kyuseokkim rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT dooryeonchung rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT inyoungyoo rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT heejaehuh rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT hyunseokmin rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT namyonglee rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork
AT yongkeunpark rapidspeciesidentificationofpathogenicbacteriafromaminutequantityexploitingthreedimensionalquantitativephaseimagingandartificialneuralnetwork