EVALUATION OF SOME ANTIOXIDANTS’ EFFECTS IN KIDNEY HISTOLOGICAL STRUCTURE OF WEANED PIGS, INTOXICATED WITH DEOXYNIVALENOL (DON)
Deoxynivalenol is a mycotoxin produced by fungi of the Fusarium genera, which are abundant in various cereal crops and processed grains. In order to protect cell structure within the tissues studied, we tried various experimental variants by incorporating some selenium and boron sources into the com...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Agroprint Timisoara
2023-11-01
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| Series: | Scientific Papers Animal Science and Biotechnologies |
| Subjects: | |
| Online Access: | https://spasb.ro/index.php/public_html/article/view/1787 |
| Summary: | Deoxynivalenol is a mycotoxin produced by fungi of the Fusarium genera, which are
abundant in various cereal crops and processed grains. In order to protect cell
structure within the tissues studied, we tried various experimental variants by
incorporating some selenium and boron sources into the combined fodder, and also
in mixture with DON with different concentrations. To determine the morphophysiological changes induced by the mycotoxin DON upon kidney histological
structure, and also the antioxidants’ effects, we took samples from 9 piglets
belonging to three groups: group 1 (fed with fodder added with DON), group 2 (fed
with fodder added with selenium) and group 3 (fed with fodder added with selenium
and DON). At renal parenchyma level, DON determines a series of changes in the
renal corpuscles and also in the uriniferous tubes. These changes are represented by
glomerular atrophies and nephrocyte epithelial dystrophies. The epithelial
dystrophic processes occur in the renal medullar, too, where numerous ectasied
capillaries and hemorrhagic areas are present. In the case of groups 2 and 3
consisted of piglets fed with fodder added with selenium, respectively fodder added
with DON and selenium, the renal vascular network becomes hypertrophic
associated with leukocyte infiltrative processes. |
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| ISSN: | 1841-9364 2344-4576 |