The predictive factors for relapses in children with steroid-sensitive nephrotic syndrome
Most patients with steroid-sensitive nephrotic syndrome (SSNS) have frequent relapses (FR); this is considered one of the main problems because of its association with a high incidence of complications. The aim of our study was to evaluate the different factors that might be associated with the occu...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Saudi Journal of Kidney Diseases and Transplantation |
| Online Access: | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2016;volume=27;issue=1;spage=67;epage=72;aulast=Ali |
| _version_ | 1818488394388340736 |
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| author | Shatha Hussain Ali Abdulkareem Mohammed Ali Abbas Hindi Najim |
| author_facet | Shatha Hussain Ali Abdulkareem Mohammed Ali Abbas Hindi Najim |
| author_sort | Shatha Hussain Ali |
| collection | DOAJ |
| description | Most patients with steroid-sensitive nephrotic syndrome (SSNS) have frequent relapses (FR); this is considered one of the main problems because of its association with a high incidence of complications. The aim of our study was to evaluate the different factors that might be associated with the occurrence of relapse in SSNS. This is a retrospective study of 80 patients with SSNS conducted at the Pediatric Nephrology Clinic in the Al-Kadhymia Teaching Hospital between January 2011 and November 2011. The study patients were divided into two groups: FR and infrequent relapses (IFR). The age of the study patients was between one and 14 years; 45 patients had FR (56.3%) and 35 patients had IFR (43.7%). Males constituted 55 patients (68.7%) and 25 patients were female (31.3%). The incidence of FR was high in all age-groups, except in the 1-5 years age-group, and was higher in children living in urban areas. There was no significant difference between the two groups in age, gender, place of residence and renal functions. However, there was a significant difference in the presence of hematuria, time taken to respond to therapy and duration of steroid therapy required; all were higher in the FR group. Our results will help clinicians in identifying possible FR such that they may be monitored closely. |
| first_indexed | 2024-12-10T16:50:32Z |
| format | Article |
| id | doaj.art-99dd64fe53204106a932f0bbf58e816b |
| institution | Directory Open Access Journal |
| issn | 1319-2442 |
| language | English |
| last_indexed | 2024-12-10T16:50:32Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Kidney Diseases and Transplantation |
| spelling | doaj.art-99dd64fe53204106a932f0bbf58e816b2022-12-22T01:40:55ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422016-01-01271677210.4103/1319-2442.174075The predictive factors for relapses in children with steroid-sensitive nephrotic syndromeShatha Hussain AliAbdulkareem Mohammed AliAbbas Hindi NajimMost patients with steroid-sensitive nephrotic syndrome (SSNS) have frequent relapses (FR); this is considered one of the main problems because of its association with a high incidence of complications. The aim of our study was to evaluate the different factors that might be associated with the occurrence of relapse in SSNS. This is a retrospective study of 80 patients with SSNS conducted at the Pediatric Nephrology Clinic in the Al-Kadhymia Teaching Hospital between January 2011 and November 2011. The study patients were divided into two groups: FR and infrequent relapses (IFR). The age of the study patients was between one and 14 years; 45 patients had FR (56.3%) and 35 patients had IFR (43.7%). Males constituted 55 patients (68.7%) and 25 patients were female (31.3%). The incidence of FR was high in all age-groups, except in the 1-5 years age-group, and was higher in children living in urban areas. There was no significant difference between the two groups in age, gender, place of residence and renal functions. However, there was a significant difference in the presence of hematuria, time taken to respond to therapy and duration of steroid therapy required; all were higher in the FR group. Our results will help clinicians in identifying possible FR such that they may be monitored closely.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2016;volume=27;issue=1;spage=67;epage=72;aulast=Ali |
| spellingShingle | Shatha Hussain Ali Abdulkareem Mohammed Ali Abbas Hindi Najim The predictive factors for relapses in children with steroid-sensitive nephrotic syndrome Saudi Journal of Kidney Diseases and Transplantation |
| title | The predictive factors for relapses in children with steroid-sensitive nephrotic syndrome |
| title_full | The predictive factors for relapses in children with steroid-sensitive nephrotic syndrome |
| title_fullStr | The predictive factors for relapses in children with steroid-sensitive nephrotic syndrome |
| title_full_unstemmed | The predictive factors for relapses in children with steroid-sensitive nephrotic syndrome |
| title_short | The predictive factors for relapses in children with steroid-sensitive nephrotic syndrome |
| title_sort | predictive factors for relapses in children with steroid sensitive nephrotic syndrome |
| url | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2016;volume=27;issue=1;spage=67;epage=72;aulast=Ali |
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