Inflammation-induced PINCH expression leads to actin depolymerization and mitochondrial mislocalization in neurons

Inflammation-induced PINCH expression leads to actin depolymerization and mitochondrial mislocalization in neurons

Abstract Background Diseases and disorders with a chronic neuroinflammatory component are often linked with changes in brain metabolism. Among neurodegenerative disorders, people living with human immunodeficiency virus (HIV) and Alzheimer’s disease (AD) are particularly vulnerable to metabolic dist...

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Bibliographic Details
Main Authors: Kalimuthusamy Natarajaseenivasan, Santhanam Shanmughapriya, Prema Velusamy, Matthew Sayre, Alvaro Garcia, Nestor Mas Gomez, Dianne Langford
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Translational Neurodegeneration
Subjects:
Neuron
Mitochondria
Actin
PINCH
Neuroinflammation
Online Access:http://link.springer.com/article/10.1186/s40035-020-00211-4

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