Epidemiological features of septic nosocomial infections within various intensive care units
Background: Septic nosocomial infections are a major public health issue. Both the risk of contracting and the specificity of nosocomial pathology directly depend upon the type of inpatient settings, as well as on the institution-specific risk factors. Material and methods: The study used a descrip...
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| Format: | Article |
| Language: | English |
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Scientific Medical Association of Moldova
2023-03-01
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| Series: | The Moldovan Medical Journal |
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| Online Access: | https://moldmedjournal.md/wp-content/uploads/2023/03/moldovan-med-j-2023-66-1-prisacari-baranetchi-et-al-full-text.pdf |
| _version_ | 1797869142752100352 |
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| author | Viorel Prisacari Iana Baranețchi Marcela Chilianu Cristina Rarancean |
| author_facet | Viorel Prisacari Iana Baranețchi Marcela Chilianu Cristina Rarancean |
| author_sort | Viorel Prisacari |
| collection | DOAJ |
| description | Background: Septic nosocomial infections are a major public health issue. Both the risk of contracting and the specificity of nosocomial pathology directly depend upon the type of inpatient settings, as well as on the institution-specific risk factors.
Material and methods: The study used a descriptive observation method based on a cross-sectional study. The present research documented and analysed retrospectively 687 follow-up records of patients admitted to different intensive care units.
Results: The study results found that the incidence of septic nosocomial infection within various intensive care units (ICU) differs, ranging between 24.68% up to 34.8%. The structure of nosological forms was dominated by severe infections as pneumonia – 50.7%, septicemia – 12.68%, surgical site infections – 12.60%, urinary tract infections – 8.45%. The polyetiological structure of pathogens varied depending on the types of ICU. Microorganisms of the genus Staphylococcus, Acinetobacter, Clebsiella, Pseudomonas and Enterobacter predominated in most gram-negative (87.25%) cases, being multi-drug resistant to antibiotics. The following risk factors for the development of nosocomial septic infections were identified: the widespread use of invasive devices in the treatment process, patient’s comorbidities, polytraumas, vasopressors administration, the length of hospital stay within the ICU, etc. The clinical and economic effect is also important; hence the hospital stay length of patients with nosocomial infections was 2.2-2.5 times, the hospital stay cost per patient was 4.56 times, and the mortality rate was 4.55-8.43 higher compared to patients with no purulent nosocomial infections.
Conclusions: Septic nosocomial infections are an urgent issue for ICU admission, which requires the implementation of comprehensive programs to prevent morbidity and reduce microbial antibiotic resistance. |
| first_indexed | 2024-04-10T00:08:00Z |
| format | Article |
| id | doaj.art-99de08450629477daa1e648ebe137df9 |
| institution | Directory Open Access Journal |
| issn | 2537-6373 2537-6381 |
| language | English |
| last_indexed | 2024-04-10T00:08:00Z |
| publishDate | 2023-03-01 |
| publisher | Scientific Medical Association of Moldova |
| record_format | Article |
| series | The Moldovan Medical Journal |
| spelling | doaj.art-99de08450629477daa1e648ebe137df92023-03-16T19:24:54ZengScientific Medical Association of MoldovaThe Moldovan Medical Journal2537-63732537-63812023-03-01661512https://doi.org/10.52418/moldovan-med-j.66-1.23.01Epidemiological features of septic nosocomial infections within various intensive care unitsViorel Prisacari0https://orcid.org/0000-0002-8694-2327Iana Baranețchi1https://orcid.org/0000-0002-2899-6482Marcela Chilianu2https://orcid.org/0000-0002-0250-6684Cristina Rarancean3https://orcid.org/0000-0002-1598-5901Nicolae Testemitanu State University of Medicine and Pharmacy Chisinau, the Republic of MoldovaNicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, the Republic of MoldovaNicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, the Republic of MoldovaNicolae Testemitanu State University of Medicine and Pharmacy, Chisinau, the Republic of MoldovaBackground: Septic nosocomial infections are a major public health issue. Both the risk of contracting and the specificity of nosocomial pathology directly depend upon the type of inpatient settings, as well as on the institution-specific risk factors. Material and methods: The study used a descriptive observation method based on a cross-sectional study. The present research documented and analysed retrospectively 687 follow-up records of patients admitted to different intensive care units. Results: The study results found that the incidence of septic nosocomial infection within various intensive care units (ICU) differs, ranging between 24.68% up to 34.8%. The structure of nosological forms was dominated by severe infections as pneumonia – 50.7%, septicemia – 12.68%, surgical site infections – 12.60%, urinary tract infections – 8.45%. The polyetiological structure of pathogens varied depending on the types of ICU. Microorganisms of the genus Staphylococcus, Acinetobacter, Clebsiella, Pseudomonas and Enterobacter predominated in most gram-negative (87.25%) cases, being multi-drug resistant to antibiotics. The following risk factors for the development of nosocomial septic infections were identified: the widespread use of invasive devices in the treatment process, patient’s comorbidities, polytraumas, vasopressors administration, the length of hospital stay within the ICU, etc. The clinical and economic effect is also important; hence the hospital stay length of patients with nosocomial infections was 2.2-2.5 times, the hospital stay cost per patient was 4.56 times, and the mortality rate was 4.55-8.43 higher compared to patients with no purulent nosocomial infections. Conclusions: Septic nosocomial infections are an urgent issue for ICU admission, which requires the implementation of comprehensive programs to prevent morbidity and reduce microbial antibiotic resistance. https://moldmedjournal.md/wp-content/uploads/2023/03/moldovan-med-j-2023-66-1-prisacari-baranetchi-et-al-full-text.pdfnosocomial septic infectionsintensive care unitsepidemiologyetiologyrisk factors |
| spellingShingle | Viorel Prisacari Iana Baranețchi Marcela Chilianu Cristina Rarancean Epidemiological features of septic nosocomial infections within various intensive care units The Moldovan Medical Journal nosocomial septic infections intensive care units epidemiology etiology risk factors |
| title | Epidemiological features of septic nosocomial infections within various intensive care units |
| title_full | Epidemiological features of septic nosocomial infections within various intensive care units |
| title_fullStr | Epidemiological features of septic nosocomial infections within various intensive care units |
| title_full_unstemmed | Epidemiological features of septic nosocomial infections within various intensive care units |
| title_short | Epidemiological features of septic nosocomial infections within various intensive care units |
| title_sort | epidemiological features of septic nosocomial infections within various intensive care units |
| topic | nosocomial septic infections intensive care units epidemiology etiology risk factors |
| url | https://moldmedjournal.md/wp-content/uploads/2023/03/moldovan-med-j-2023-66-1-prisacari-baranetchi-et-al-full-text.pdf |
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