Therapeutic Failure and Acquired Bedaquiline and Delamanid Resistance in Treatment of Drug-Resistant TB
New classes of antitubercular drugs, diarylquinolines and nitroimidazoles, have been associated with improved outcomes in the treatment of drug-resistant tuberculosis, but that success is threatened by emerging drug resistance. We report a case of bedaquiline and delamanid resistance in a 55-year-o...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2023-05-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/29/5/22-1716_article |
| _version_ | 1797843456047972352 |
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| author | James Millard Stephanie Rimmer Camus Nimmo Max O’Donnell |
| author_facet | James Millard Stephanie Rimmer Camus Nimmo Max O’Donnell |
| author_sort | James Millard |
| collection | DOAJ |
| description |
New classes of antitubercular drugs, diarylquinolines and nitroimidazoles, have been associated with improved outcomes in the treatment of drug-resistant tuberculosis, but that success is threatened by emerging drug resistance. We report a case of bedaquiline and delamanid resistance in a 55-year-old woman in South Africa with extensively drug-resistant tuberculosis and known HIV.
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| first_indexed | 2024-04-09T17:05:33Z |
| format | Article |
| id | doaj.art-99de67ef3f8c4beaa458c56f115b9422 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-04-09T17:05:33Z |
| publishDate | 2023-05-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-99de67ef3f8c4beaa458c56f115b94222023-04-20T14:28:15ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592023-05-012951081108410.3201/eid2905.221716Therapeutic Failure and Acquired Bedaquiline and Delamanid Resistance in Treatment of Drug-Resistant TBJames MillardStephanie RimmerCamus NimmoMax O’Donnell New classes of antitubercular drugs, diarylquinolines and nitroimidazoles, have been associated with improved outcomes in the treatment of drug-resistant tuberculosis, but that success is threatened by emerging drug resistance. We report a case of bedaquiline and delamanid resistance in a 55-year-old woman in South Africa with extensively drug-resistant tuberculosis and known HIV. https://wwwnc.cdc.gov/eid/article/29/5/22-1716_articletuberculosis and other mycobacteriabacteriaantimicrobial resistancebedaquilinedelamanidXDR TB |
| spellingShingle | James Millard Stephanie Rimmer Camus Nimmo Max O’Donnell Therapeutic Failure and Acquired Bedaquiline and Delamanid Resistance in Treatment of Drug-Resistant TB Emerging Infectious Diseases tuberculosis and other mycobacteria bacteria antimicrobial resistance bedaquiline delamanid XDR TB |
| title | Therapeutic Failure and Acquired Bedaquiline and Delamanid Resistance in Treatment of Drug-Resistant TB |
| title_full | Therapeutic Failure and Acquired Bedaquiline and Delamanid Resistance in Treatment of Drug-Resistant TB |
| title_fullStr | Therapeutic Failure and Acquired Bedaquiline and Delamanid Resistance in Treatment of Drug-Resistant TB |
| title_full_unstemmed | Therapeutic Failure and Acquired Bedaquiline and Delamanid Resistance in Treatment of Drug-Resistant TB |
| title_short | Therapeutic Failure and Acquired Bedaquiline and Delamanid Resistance in Treatment of Drug-Resistant TB |
| title_sort | therapeutic failure and acquired bedaquiline and delamanid resistance in treatment of drug resistant tb |
| topic | tuberculosis and other mycobacteria bacteria antimicrobial resistance bedaquiline delamanid XDR TB |
| url | https://wwwnc.cdc.gov/eid/article/29/5/22-1716_article |
| work_keys_str_mv | AT jamesmillard therapeuticfailureandacquiredbedaquilineanddelamanidresistanceintreatmentofdrugresistanttb AT stephanierimmer therapeuticfailureandacquiredbedaquilineanddelamanidresistanceintreatmentofdrugresistanttb AT camusnimmo therapeuticfailureandacquiredbedaquilineanddelamanidresistanceintreatmentofdrugresistanttb AT maxodonnell therapeuticfailureandacquiredbedaquilineanddelamanidresistanceintreatmentofdrugresistanttb |