PMA activation of macrophages alters macrophage metabolism of aggregated LDL

PMA activation of macrophages alters macrophage metabolism of aggregated LDL

Aggregation of LDL may contribute to its retention in atherosclerotic lesions. Previously, we showed that aggregated LDL induces and enters surface-connected compartments (SCCs) in human monocyte-derived macrophages by a process we have named patocytosis. Aggregated LDL was disaggregated and release...

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Bibliographic Details
Main Authors: Wei Huang, Itsuko Ishii, Wei-Yang Zhang, Miyahiko Sonobe, Howard S. Kruth
Format: Article
Language:English
Published: Elsevier 2002-08-01
Series:Journal of Lipid Research
Subjects:
acyl-CoA:cholesterol acyltransferase
atherosclerosis
cholesterol
endocytosis
plasmin
low density lipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520300596

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