Pleomorphic adenoma of the parotid gland concomitant with tuberculosis infection: A case report and review of the literature

Tuberculosis of the salivary glands and particularly of the parotid gland is a localization that remains rare even in endemic countries. The association of intra parotid tuberculosis with a benign tumor has been found only in rare cases in literature. A 50-year-old woman with a history of normal pre...

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Main Authors: Dorra Chiboub, Nadia Romdhane, Esma Jameleddine, Emna Rejeb, Fatma Khanchel, Raja Jouini, Imen Zoghlami, Safa Nefzaoui, Ines Hariga, Chiraz Mbarek
Format: Article
Language:English
Published: SAGE Publishing 2024-03-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X241236153
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author Dorra Chiboub
Nadia Romdhane
Esma Jameleddine
Emna Rejeb
Fatma Khanchel
Raja Jouini
Imen Zoghlami
Safa Nefzaoui
Ines Hariga
Chiraz Mbarek
author_facet Dorra Chiboub
Nadia Romdhane
Esma Jameleddine
Emna Rejeb
Fatma Khanchel
Raja Jouini
Imen Zoghlami
Safa Nefzaoui
Ines Hariga
Chiraz Mbarek
author_sort Dorra Chiboub
collection DOAJ
description Tuberculosis of the salivary glands and particularly of the parotid gland is a localization that remains rare even in endemic countries. The association of intra parotid tuberculosis with a benign tumor has been found only in rare cases in literature. A 50-year-old woman with a history of normal pressure hydrocephalus treated surgically, non-smoker, presented with a right parotid swelling progressively increasing in size for 3 years. Clinical examination revealed a 4 cm long, firm, mobile, painless parotid swelling without inflammatory signs and without accessory lymphadenopathy. The oropharyngeal examination was without abnormalities. Ultrasound showed a mass of 31 × 27 mm suggesting a pleomorphic adenoma. MRI confirmed the suspicion of a pleomorphic adenoma of both lobes. The patient underwent a conservative total parotidectomy. The extemporaneous examination was in favor of a pleomorphic adenoma while the final pathology showed the coexistence of active tuberculosis lesions. The patient was put on long-term antituberculosis treatment with good clinical evolution. The clinical presentation of parotid tuberculosis is nonspecific mimicking any other tumor and the diagnosis can only be made by histological examination. Therapeutic management is based on long-term antituberculosis treatment.
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spelling doaj.art-99e30736a4d24b98ac1ab18a5a0e79632024-03-04T18:03:24ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2024-03-011210.1177/2050313X241236153Pleomorphic adenoma of the parotid gland concomitant with tuberculosis infection: A case report and review of the literatureDorra Chiboub0Nadia Romdhane1Esma Jameleddine2Emna Rejeb3Fatma Khanchel4Raja Jouini5Imen Zoghlami6Safa Nefzaoui7Ines Hariga8Chiraz Mbarek9Department of Otorhinolaryngology, Head and Neck Surgery, Habib Thameur Hospital, Tunis, TunisiaDepartment of Otorhinolaryngology, Head and Neck Surgery, Habib Thameur Hospital, Tunis, TunisiaDepartment of Otorhinolaryngology, Head and Neck Surgery, Habib Thameur Hospital, Tunis, TunisiaDepartment of Otorhinolaryngology, Head and Neck Surgery, Habib Thameur Hospital, Tunis, TunisiaDepartment of Pathology, Habib Thameur Hospital, Tunis, TunisiaDepartment of Pathology, Habib Thameur Hospital, Tunis, TunisiaDepartment of Otorhinolaryngology, Head and Neck Surgery, Habib Thameur Hospital, Tunis, TunisiaDepartment of Otorhinolaryngology, Head and Neck Surgery, Habib Thameur Hospital, Tunis, TunisiaDepartment of Otorhinolaryngology, Head and Neck Surgery, Habib Thameur Hospital, Tunis, TunisiaDepartment of Otorhinolaryngology, Head and Neck Surgery, Habib Thameur Hospital, Tunis, TunisiaTuberculosis of the salivary glands and particularly of the parotid gland is a localization that remains rare even in endemic countries. The association of intra parotid tuberculosis with a benign tumor has been found only in rare cases in literature. A 50-year-old woman with a history of normal pressure hydrocephalus treated surgically, non-smoker, presented with a right parotid swelling progressively increasing in size for 3 years. Clinical examination revealed a 4 cm long, firm, mobile, painless parotid swelling without inflammatory signs and without accessory lymphadenopathy. The oropharyngeal examination was without abnormalities. Ultrasound showed a mass of 31 × 27 mm suggesting a pleomorphic adenoma. MRI confirmed the suspicion of a pleomorphic adenoma of both lobes. The patient underwent a conservative total parotidectomy. The extemporaneous examination was in favor of a pleomorphic adenoma while the final pathology showed the coexistence of active tuberculosis lesions. The patient was put on long-term antituberculosis treatment with good clinical evolution. The clinical presentation of parotid tuberculosis is nonspecific mimicking any other tumor and the diagnosis can only be made by histological examination. Therapeutic management is based on long-term antituberculosis treatment.https://doi.org/10.1177/2050313X241236153
spellingShingle Dorra Chiboub
Nadia Romdhane
Esma Jameleddine
Emna Rejeb
Fatma Khanchel
Raja Jouini
Imen Zoghlami
Safa Nefzaoui
Ines Hariga
Chiraz Mbarek
Pleomorphic adenoma of the parotid gland concomitant with tuberculosis infection: A case report and review of the literature
SAGE Open Medical Case Reports
title Pleomorphic adenoma of the parotid gland concomitant with tuberculosis infection: A case report and review of the literature
title_full Pleomorphic adenoma of the parotid gland concomitant with tuberculosis infection: A case report and review of the literature
title_fullStr Pleomorphic adenoma of the parotid gland concomitant with tuberculosis infection: A case report and review of the literature
title_full_unstemmed Pleomorphic adenoma of the parotid gland concomitant with tuberculosis infection: A case report and review of the literature
title_short Pleomorphic adenoma of the parotid gland concomitant with tuberculosis infection: A case report and review of the literature
title_sort pleomorphic adenoma of the parotid gland concomitant with tuberculosis infection a case report and review of the literature
url https://doi.org/10.1177/2050313X241236153
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